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Symmetry and interhemispheric propagation of paediatric photoparoxysmal response
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Affiliations- Department of Pediatric Neurosurgery, Bogdanowicz Memorial Hospital for Children, Nieklanska 4/24, 03-924 Warsaw, Poland
- Department of Descriptive and Clinical Anatomy, Centre of Biostructure Research Medical University of Warsaw, Poland, Chalubinskiego 5, 02-004 Warszaw, Poland
- Department of Pediatric Neurology, Medical University of Warsaw, 63A Zwirki i Wigury St., 02-091 Warsaw, Poland
- EEG Laboratory, Bogdanowicz Memorial Hospital for Children, 4/24 Nieklanska St., 03-924 Warsaw, Poland
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Abstract
Aim of the study. To investigate the speculated interhemispheric symmetry and the pattern of propagation of paediatric photoparoxysmal response.
Clinical rationale for the study. Quantitative analysis of the photoparoxysmal response (PPR) to intermittent photic stimulation is a promising method of assessing photosensitivity (PS). The pattern of PPR propagation underlies the model used for calculations. The generalisation of a discharge should correspond with the parameters objectively characterising the PPR in both cerebral hemispheres. However, to date no evidence of a postulated symmetry has been demonstrated.
Materials and methods. Our analysis was performed by comparing the EEG amplitude and interhemispheric coherence (ICoh) in both hemispheres in 100 non-epileptic individuals of both sexes, aged 5–18 years, with PS grade IV (the PPR group) and without PS (the control group). The amplitude and ICoh values were recorded and analysed statistically.
Results. The distribution of amplitude values between the hemispheres was comparable in both groups, but was significantly different between the PPR group and the control group. Individual tracks of propagation revealed hemispheric symmetry. Interhemispheric coherence values were significantly higher in occipital, temporal and fronto-polar areas in children with PS.
Conclusions and clinical implications. This study provides objective evidence of interhemispheric symmetry in paediatric PPR, which supports the link with generalised seizures. Interhemispheric propagation is facilitated in children with PS, and propagation is more likely in the occipital and temporal regions.
Abstract
Aim of the study. To investigate the speculated interhemispheric symmetry and the pattern of propagation of paediatric photoparoxysmal response.
Clinical rationale for the study. Quantitative analysis of the photoparoxysmal response (PPR) to intermittent photic stimulation is a promising method of assessing photosensitivity (PS). The pattern of PPR propagation underlies the model used for calculations. The generalisation of a discharge should correspond with the parameters objectively characterising the PPR in both cerebral hemispheres. However, to date no evidence of a postulated symmetry has been demonstrated.
Materials and methods. Our analysis was performed by comparing the EEG amplitude and interhemispheric coherence (ICoh) in both hemispheres in 100 non-epileptic individuals of both sexes, aged 5–18 years, with PS grade IV (the PPR group) and without PS (the control group). The amplitude and ICoh values were recorded and analysed statistically.
Results. The distribution of amplitude values between the hemispheres was comparable in both groups, but was significantly different between the PPR group and the control group. Individual tracks of propagation revealed hemispheric symmetry. Interhemispheric coherence values were significantly higher in occipital, temporal and fronto-polar areas in children with PS.
Conclusions and clinical implications. This study provides objective evidence of interhemispheric symmetry in paediatric PPR, which supports the link with generalised seizures. Interhemispheric propagation is facilitated in children with PS, and propagation is more likely in the occipital and temporal regions.
Keywords
photoparoxysmal response, photosensitivity, interhemispheric symmetry, interhemispheric coherence
About this articleTitle
Symmetry and interhemispheric propagation of paediatric photoparoxysmal response
Journal
Neurologia i Neurochirurgia Polska
Issue
Article type
Research Paper
Pages
193-199
Published online
2020-04-08
Page views
828
Article views/downloads
364
DOI
Pubmed
Bibliographic record
Neurol Neurochir Pol 2020;54(2):193-199.
Keywords
photoparoxysmal response
photosensitivity
interhemispheric symmetry
interhemispheric coherence
Authors
Tymon Skadorwa
Jolanta Strzelecka
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