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Clinical value of 99Tcm-MIBI gated myocardial perfusion imaging in evaluating sarcoglycanopathy
Affiliations- Dapartment of Nuclear Medicine, the third Hospital of Hebei Medical University, 050051 Shijiazhuang, China
- Dapartment of Neuromuscular Disorder, the third Hospital of Hebei Medical University,, Shijiazhuang, China
open access
Abstract
Aim. The purpose of this study was to analyse the diagnostic value of gated myocardial perfusion imaging (G-MPI) in the evaluation of myocardial injury in sarcoglycanopathy.
Materials and methods. Twenty-eight patients diagnosed with sarcoglycanopathy were evaluated using 99m-
-methoxyisobutylisonitrile(99Tcm-MIBI) G-MPI. The data was processed into tomographic images, and the left ventricular function was analysed using quantitative gated SPECT (QGS) to assess the degree of impairment in myocardial and cardiac function.
Results. The images of 23 of the patients (82.1%) were positive. Two hundred and twenty-nine sub-segments with abnormal lesions were detected out of 391 cardiac sub-segments of these 23 positive cases. According to the segmental abnormalities, the cases were divided into two cases (8.7%) with single abnormal wall segment, six cases (26.1%) with two abnormal wall segments, and 15 cases (65.2%) with three or more abnormal wall segments or scattered lesions.
Conclusions. 99Tcm-MIBI G-MPI can objectively show impaired myocardium in patients with sarcoglycanopathy. Therefore, this method is helpful for early diagnosis and follow-up of myocardial damage.
Abstract
Aim. The purpose of this study was to analyse the diagnostic value of gated myocardial perfusion imaging (G-MPI) in the evaluation of myocardial injury in sarcoglycanopathy.
Materials and methods. Twenty-eight patients diagnosed with sarcoglycanopathy were evaluated using 99m-
-methoxyisobutylisonitrile(99Tcm-MIBI) G-MPI. The data was processed into tomographic images, and the left ventricular function was analysed using quantitative gated SPECT (QGS) to assess the degree of impairment in myocardial and cardiac function.
Results. The images of 23 of the patients (82.1%) were positive. Two hundred and twenty-nine sub-segments with abnormal lesions were detected out of 391 cardiac sub-segments of these 23 positive cases. According to the segmental abnormalities, the cases were divided into two cases (8.7%) with single abnormal wall segment, six cases (26.1%) with two abnormal wall segments, and 15 cases (65.2%) with three or more abnormal wall segments or scattered lesions.
Conclusions. 99Tcm-MIBI G-MPI can objectively show impaired myocardium in patients with sarcoglycanopathy. Therefore, this method is helpful for early diagnosis and follow-up of myocardial damage.
Keywords
Sarcoglycanopathy, tomography, emission computer, single photon, MIBI
About this articleTitle
Clinical value of 99Tcm-MIBI gated myocardial perfusion imaging in evaluating sarcoglycanopathy
Journal
Neurologia i Neurochirurgia Polska
Issue
Article type
Research Paper
Pages
265-270
Published online
2019-07-25
Page views
1006
Article views/downloads
261
DOI
Pubmed
Bibliographic record
Neurol Neurochir Pol 2019;53(4):265-270.
Keywords
Sarcoglycanopathy
tomography
emission computer
single photon
MIBI
Authors
Peng Fu
Ling-Ge Wei
Jing Hu
Jian-Qing Gao
Jian-Min Jing
Xiao-Mei Liu
Jian-Min Huang
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