Vol 53, No 4 (2019)
Research paper
Published online: 2019-07-25
Submitted: 2019-01-27
Accepted: 2019-06-21
Get Citation

Clinical value of 99Tcm-MIBI gated myocardial perfusion imaging in evaluating sarcoglycanopathy

Peng Fu, Ling-Ge Wei, Jing Hu, Jian-Qing Gao, Jian-Min Jing, Xiao-Mei Liu, Jian-Min Huang
DOI: 10.5603/PJNNS.a2019.0027
·
Pubmed: 31343070
·
Neurol Neurochir Pol 2019;53(4):265-270.

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Vol 53, No 4 (2019)
Research paper
Published online: 2019-07-25
Submitted: 2019-01-27
Accepted: 2019-06-21

Abstract

Aim. The purpose of this study was to analyse the diagnostic value of gated myocardial perfusion imaging (G-MPI) in the evaluation of myocardial injury in sarcoglycanopathy.

Materials and methods. Twenty-eight patients diagnosed with sarcoglycanopathy were evaluated using 99m-
-methoxyisobutylisonitrile(99Tcm-MIBI) G-MPI. The data was processed into tomographic images, and the left ventricular function was analysed using quantitative gated SPECT (QGS) to assess the degree of impairment in myocardial and cardiac function.

Results. The images of 23 of the patients (82.1%) were positive. Two hundred and twenty-nine sub-segments with abnormal lesions were detected out of 391 cardiac sub-segments of these 23 positive cases. According to the segmental abnormalities, the cases were divided into two cases (8.7%) with single abnormal wall segment, six cases (26.1%) with two abnormal wall segments, and 15 cases (65.2%) with three or more abnormal wall segments or scattered lesions.

Conclusions. 99Tcm-MIBI G-MPI can objectively show impaired myocardium in patients with sarcoglycanopathy. Therefore, this method is helpful for early diagnosis and follow-up of myocardial damage.

Abstract

Aim. The purpose of this study was to analyse the diagnostic value of gated myocardial perfusion imaging (G-MPI) in the evaluation of myocardial injury in sarcoglycanopathy.

Materials and methods. Twenty-eight patients diagnosed with sarcoglycanopathy were evaluated using 99m-
-methoxyisobutylisonitrile(99Tcm-MIBI) G-MPI. The data was processed into tomographic images, and the left ventricular function was analysed using quantitative gated SPECT (QGS) to assess the degree of impairment in myocardial and cardiac function.

Results. The images of 23 of the patients (82.1%) were positive. Two hundred and twenty-nine sub-segments with abnormal lesions were detected out of 391 cardiac sub-segments of these 23 positive cases. According to the segmental abnormalities, the cases were divided into two cases (8.7%) with single abnormal wall segment, six cases (26.1%) with two abnormal wall segments, and 15 cases (65.2%) with three or more abnormal wall segments or scattered lesions.

Conclusions. 99Tcm-MIBI G-MPI can objectively show impaired myocardium in patients with sarcoglycanopathy. Therefore, this method is helpful for early diagnosis and follow-up of myocardial damage.

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Keywords

Sarcoglycanopathy, tomography, emission computer, single photon, MIBI

About this article
Title

Clinical value of 99Tcm-MIBI gated myocardial perfusion imaging in evaluating sarcoglycanopathy

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 53, No 4 (2019)

Pages

265-270

Published online

2019-07-25

DOI

10.5603/PJNNS.a2019.0027

Pubmed

31343070

Bibliographic record

Neurol Neurochir Pol 2019;53(4):265-270.

Keywords

Sarcoglycanopathy
tomography
emission computer
single photon
MIBI

Authors

Peng Fu
Ling-Ge Wei
Jing Hu
Jian-Qing Gao
Jian-Min Jing
Xiao-Mei Liu
Jian-Min Huang

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