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Which came first, the risk of migraine or the risk of asthma? A systematic review
Affiliations- Education Development Center (EDC), Psychiatrist, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic Of
- Department of Biostatistics and Epidemiology, Faculty of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz
- Department of Emergency Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic Of
- Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Ahvaz, Iran, Islamic Republic Of
- Research Center of Thalassemia & Hemoglobinopathy, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Islamic Republic Of
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Abstract
We conducted this review to systematically assess the association and risk of the migraine in the patient with asthma and vice versa.
MethodsWe systematically searched publishes articles indexed in PubMed, Scopus, Cochrane library, PsycINFO, CINAHL, ISI Web of Science, Science Direct from inception, and Embase databases until June 2017. The quality assessment of the involved studies was done using the Newcastle-Ottawa Scale (NOS).
ResultsEight studies with 389,573 participants were reviewed and selected for data extraction. Among the selected studies, 5 were reported the association between migraine with asthma risk, and the rest three studies reported the risk of asthma in patient with migraine compared to non-moraine individuals. Odds ratio (OR) of migraine for patient with asthma as compared with non-asthmatic individuals was 1.62 (95% CI 1.43–1.82). Data pooling using a random-effect model showed that migraine was associated with a significant increased risk of asthma (relative risk (RR): 1.56; 95% CI: 1.51–1.60; p < .00001). Besides, sub-group and sensitivity analyses supported the positive association between asthma and migraine, and risk of asthma in migraine patients.
ConclusionNow it is unknown if control of the asthma will impact the severity of migraines or vice versa, but it is necessary to perform more research to further explain the mechanisms through which asthma increases the frequency of migraine or vice versa. If two conditions linked, once an individual undergo better control of asthma symptoms, might the excruciating migraine ease, too.
Abstract
We conducted this review to systematically assess the association and risk of the migraine in the patient with asthma and vice versa.
MethodsWe systematically searched publishes articles indexed in PubMed, Scopus, Cochrane library, PsycINFO, CINAHL, ISI Web of Science, Science Direct from inception, and Embase databases until June 2017. The quality assessment of the involved studies was done using the Newcastle-Ottawa Scale (NOS).
ResultsEight studies with 389,573 participants were reviewed and selected for data extraction. Among the selected studies, 5 were reported the association between migraine with asthma risk, and the rest three studies reported the risk of asthma in patient with migraine compared to non-moraine individuals. Odds ratio (OR) of migraine for patient with asthma as compared with non-asthmatic individuals was 1.62 (95% CI 1.43–1.82). Data pooling using a random-effect model showed that migraine was associated with a significant increased risk of asthma (relative risk (RR): 1.56; 95% CI: 1.51–1.60; p < .00001). Besides, sub-group and sensitivity analyses supported the positive association between asthma and migraine, and risk of asthma in migraine patients.
ConclusionNow it is unknown if control of the asthma will impact the severity of migraines or vice versa, but it is necessary to perform more research to further explain the mechanisms through which asthma increases the frequency of migraine or vice versa. If two conditions linked, once an individual undergo better control of asthma symptoms, might the excruciating migraine ease, too.
Keywords
MOOSE, PRISMA, NOS, OR, RR, HR, CI
About this articleTitle
Which came first, the risk of migraine or the risk of asthma? A systematic review
Journal
Neurologia i Neurochirurgia Polska
Issue
Article type
Review Article
Pages
562-569
Published online
2018-08-03
Page views
267
Article views/downloads
442
DOI
10.1016/j.pjnns.2018.07.004
Bibliographic record
Neurol Neurochir Pol 2018;52(5):562-569.
Keywords
MOOSE
PRISMA
NOS
OR
RR
HR
CI
Authors
Mehdi Sayyah
Amal Saki-Malehi
Fatemeh Javanmardi
Arash Forouzan
Kiarash Shirbandi
Fakher Rahim
