open access

Vol 52, No 4 (2018)
Short communications
Submitted: 2018-04-21
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The impact of subthalamic deep brain stimulation on polysomnographic sleep pattern in patients with Parkinson's disease – Preliminary report

Jarosław Dulski, Michał Schinwelski, Agnieszka Konkel, Karol Grabowski, Witold Libionka, Piotr Wąż, Sitek E.J., Jarosław Sławek
DOI: 10.1016/j.pjnns.2018.05.006
·
Neurol Neurochir Pol 2018;52(4):514-518.

open access

Vol 52, No 4 (2018)
Short communications
Submitted: 2018-04-21

Abstract

Aim of the study

We present the preliminary results of the study focused on the impact of subthalamic deep brain stimulation (DBS-STN) on sleep and other non-motor symptoms (NMS).

Materials and methods

Ten patients with advanced PD, underwent two-night polysomnography (PSG) mean 1.1 week before surgery and 6.2 months post DBS programming. NMS were assessed with a set of scales before surgery and 6 months and 12 months following DBS programming.

Results

Contrary to previous studies, we noted deterioration of sleep pattern in the follow-up PSG. We found a decrease in total sleep time, duration of the stage N2, with prolongation of stage N1 and wakefulness after sleep onset. We did not detect any impact of DBS-STN on subjective severity of restless legs syndrome. REM – sleep behavior disorder, however reported was not observed in any patient during PSG evaluations. We also found statistically significant correlations between severity of sleep disturbances and quality of life, as well as, between severity of motor symptoms and worse objective sleep quality.

Conclusions

We found that DBS-STN improved quality of life, subjective quality of sleep and sleepiness, however, contrary to the previous studies the objective parameters of sleep worsened after the surgery.

Abstract

Aim of the study

We present the preliminary results of the study focused on the impact of subthalamic deep brain stimulation (DBS-STN) on sleep and other non-motor symptoms (NMS).

Materials and methods

Ten patients with advanced PD, underwent two-night polysomnography (PSG) mean 1.1 week before surgery and 6.2 months post DBS programming. NMS were assessed with a set of scales before surgery and 6 months and 12 months following DBS programming.

Results

Contrary to previous studies, we noted deterioration of sleep pattern in the follow-up PSG. We found a decrease in total sleep time, duration of the stage N2, with prolongation of stage N1 and wakefulness after sleep onset. We did not detect any impact of DBS-STN on subjective severity of restless legs syndrome. REM – sleep behavior disorder, however reported was not observed in any patient during PSG evaluations. We also found statistically significant correlations between severity of sleep disturbances and quality of life, as well as, between severity of motor symptoms and worse objective sleep quality.

Conclusions

We found that DBS-STN improved quality of life, subjective quality of sleep and sleepiness, however, contrary to the previous studies the objective parameters of sleep worsened after the surgery.

Get Citation

Keywords

Parkinson' s disease, Deep brain stimulation, Sleep, Quality of life, Polysomnography

About this article
Title

The impact of subthalamic deep brain stimulation on polysomnographic sleep pattern in patients with Parkinson's disease – Preliminary report

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 52, No 4 (2018)

Pages

514-518

DOI

10.1016/j.pjnns.2018.05.006

Bibliographic record

Neurol Neurochir Pol 2018;52(4):514-518.

Keywords

Parkinson's disease
Deep brain stimulation
Sleep
Quality of life
Polysomnography

Authors

Jarosław Dulski
Michał Schinwelski
Agnieszka Konkel
Karol Grabowski
Witold Libionka
Piotr Wąż
Sitek E.J.
Jarosław Sławek

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