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Intraventricular treatment of secondary central nervous system lymphoma – Case study and literature overview
Affiliations- Chair and Department of Neurosurgery and Paediatric Neurosurgery Medical University of Lublin, Poland
- Chair and Department of Haematooncology and Bone Marrow Transplantation Medical University of Lublin, Poland
- Independent Clinical Transplantology Unit Medical University of Lublin, Poland
- Chair and Department of Clinical Immunology Medical University of Lublin, Poland
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Abstract
Secondary nervous system lymphoma (SCNSL) is a rare extranodal form of non-Hodgkin lymphoma (NHL). This applies to a particular form of lymphoma that does not originally derive from the central nervous system (CNS); it can be both an isolated form of relapse or a systemic part of disease progression. Due to poor prognosis and a lack of established algorithms of therapeutic procedures, it is a big challenge for physicians from many specializations. In our study, we present an interesting case of a patient with a relapsed form of SCNSL for whom a unique form of treatment was used – intraventricular administration of rituximab and methotrexate.
Abstract
Secondary nervous system lymphoma (SCNSL) is a rare extranodal form of non-Hodgkin lymphoma (NHL). This applies to a particular form of lymphoma that does not originally derive from the central nervous system (CNS); it can be both an isolated form of relapse or a systemic part of disease progression. Due to poor prognosis and a lack of established algorithms of therapeutic procedures, it is a big challenge for physicians from many specializations. In our study, we present an interesting case of a patient with a relapsed form of SCNSL for whom a unique form of treatment was used – intraventricular administration of rituximab and methotrexate.
Keywords
Primary central nervous system lymphomas, Secondary central nervous system lymphomas, Ommaya reservoir, Intraventricular treatment
About this articleTitle
Intraventricular treatment of secondary central nervous system lymphoma – Case study and literature overview
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
410-414
Published online
2018-02-06
Page views
457
Article views/downloads
594
DOI
10.1016/j.pjnns.2018.01.007
Bibliographic record
Neurol Neurochir Pol 2018;52(3):410-414.
Keywords
Primary central nervous system lymphomas
Secondary central nervous system lymphomas
Ommaya reservoir
Intraventricular treatment
Authors
Dariusz Szczepanek
Ewa Wąsik-Szczepanek
Agnieszka Szymczyk
Tomasz Gromek
Ewelina Grywalska
Monika Podhorecka
Marek Hus
