open access

Vol 52, No 3 (2018)
Original research articles
Submitted: 2017-10-24
Get Citation

Intracerebral electroencephalography in targeting anterior thalamic nucleus for deep brain stimulation in refractory epilepsy

Marlena Hupalo, Rafal Wojcik, Dariusz J. Jaskolski
DOI: 10.1016/j.pjnns.2018.01.003
·
Neurol Neurochir Pol 2018;52(3):379-385.

open access

Vol 52, No 3 (2018)
Original research articles
Submitted: 2017-10-24

Abstract

Background

Results of DBS of ATN in refractory epilepsy depend on accuracy of the electrode's location. We searched for characteristic intraoperative, intracerebral EEG recording pattern from anterior thalamic nuclei (ATNs) as a biological marker for verifying the electrode's position.

Methods

There were six patients with refractory epilepsy scheduled for deep brain stimulation (DBS) procedure. At surgery, to map the target, we recorded EEG from each lead of DBS electrodes. One patient underwent a 24 hours EEG with continuous recording from both ATNs before internalization of stimulator units.

Results

In all patients we recorded spontaneous bioelectric activity of ATNs. The pattern of the recording from the ATN was similar in all cases. In the one patient where 24-hour recording was done with simultaneous scalp EEG, a complex partial seizure was captured.

Conclusion

This is the first report of using DBS electrode for intraoperative EEG recordings from the ATN in patients with refractory epilepsy. Since we managed to find the characteristic pattern of bioelectric activity of ATN, this technique seems to be a promising method for targeting this structure during the operation.

Abstract

Background

Results of DBS of ATN in refractory epilepsy depend on accuracy of the electrode's location. We searched for characteristic intraoperative, intracerebral EEG recording pattern from anterior thalamic nuclei (ATNs) as a biological marker for verifying the electrode's position.

Methods

There were six patients with refractory epilepsy scheduled for deep brain stimulation (DBS) procedure. At surgery, to map the target, we recorded EEG from each lead of DBS electrodes. One patient underwent a 24 hours EEG with continuous recording from both ATNs before internalization of stimulator units.

Results

In all patients we recorded spontaneous bioelectric activity of ATNs. The pattern of the recording from the ATN was similar in all cases. In the one patient where 24-hour recording was done with simultaneous scalp EEG, a complex partial seizure was captured.

Conclusion

This is the first report of using DBS electrode for intraoperative EEG recordings from the ATN in patients with refractory epilepsy. Since we managed to find the characteristic pattern of bioelectric activity of ATN, this technique seems to be a promising method for targeting this structure during the operation.

Get Citation

Keywords

Targeting ATN, Intracerebral EEG, DBS, Refractory epilepsy

About this article
Title

Intracerebral electroencephalography in targeting anterior thalamic nucleus for deep brain stimulation in refractory epilepsy

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 52, No 3 (2018)

Pages

379-385

DOI

10.1016/j.pjnns.2018.01.003

Bibliographic record

Neurol Neurochir Pol 2018;52(3):379-385.

Keywords

Targeting ATN
Intracerebral EEG
DBS
Refractory epilepsy

Authors

Marlena Hupalo
Rafal Wojcik
Dariusz J. Jaskolski

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