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Fatal serotonin syndrome in a patient with Marchiafava–Bignami disease: Combined neurological and psychiatric emergency
Affiliations- King Abdulaziz Medical City/King Saud bin Abdulaziz University for Health Sciences, P.O. Box: 12723, Jeddah, Saudi Arabia
- King Abdullah International Medical Research Center/King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Abstract
•In this report, we present a case with fatal serotonin syndrome happening in a non-alcoholic patient with the chronic form of MBD.•To our knowledge, this case is the first report of fatal serotonin syndrome after starting a small dose of citalopram in an MBD patient.•The present report may indicate that citalopram and other SSRIs should not be used in patients with MBD.•Our case is also among few reported cases in the literature where no cause was identified in a patient with no previous history of alcohol intake.
Abstract
•In this report, we present a case with fatal serotonin syndrome happening in a non-alcoholic patient with the chronic form of MBD.•To our knowledge, this case is the first report of fatal serotonin syndrome after starting a small dose of citalopram in an MBD patient.•The present report may indicate that citalopram and other SSRIs should not be used in patients with MBD.•Our case is also among few reported cases in the literature where no cause was identified in a patient with no previous history of alcohol intake.
Keywords
Serotonin syndrome, Marchiafava–Bignami disease, Citalopram
About this articleTitle
Fatal serotonin syndrome in a patient with Marchiafava–Bignami disease: Combined neurological and psychiatric emergency
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
277-280
Published online
2017-10-31
Page views
330
Article views/downloads
540
DOI
10.1016/j.pjnns.2017.10.011
Bibliographic record
Neurol Neurochir Pol 2018;52(2):277-280.
Keywords
Serotonin syndrome
Marchiafava–Bignami disease
Citalopram
Authors
Saeed Alghamdi
Yehya Seddeq
Hussein Algahtani
Bader Shirah
