open access

Vol 52, No 2 (2018)
Review article
Submitted: 2015-08-03
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Optical coherence tomography in diagnosis and monitoring multiple sclerosis

Jan Kucharczuk, Zdzisław Maciejek, Bartosz L. Sikorski
DOI: 10.1016/j.pjnns.2017.10.009
·
Neurol Neurochir Pol 2018;52(2):140-149.

open access

Vol 52, No 2 (2018)
Review article
Submitted: 2015-08-03

Abstract

This paper presents application of optical coherence tomography (OCT) for diagnosis and monitoring of multiple sclerosis (MS). The peripapillary retinal nerve fibre layer thinning and the reduced total macular volume analysis are shown. With the course of the MS, the severity of these abnormalities increases which reflects the progressive degeneration of retinal ganglion cells and nerve fibres. The OCT parameters are sensitive, non-invasive indicators useful in assessing the progression of inflammation and neurodegeneration in MS.

Abstract

This paper presents application of optical coherence tomography (OCT) for diagnosis and monitoring of multiple sclerosis (MS). The peripapillary retinal nerve fibre layer thinning and the reduced total macular volume analysis are shown. With the course of the MS, the severity of these abnormalities increases which reflects the progressive degeneration of retinal ganglion cells and nerve fibres. The OCT parameters are sensitive, non-invasive indicators useful in assessing the progression of inflammation and neurodegeneration in MS.

Get Citation

Keywords

Multiple sclerosis, Optical coherence tomography, Retinal nerve fiber layer, Ganglion cell layer

About this article
Title

Optical coherence tomography in diagnosis and monitoring multiple sclerosis

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 52, No 2 (2018)

Pages

140-149

DOI

10.1016/j.pjnns.2017.10.009

Bibliographic record

Neurol Neurochir Pol 2018;52(2):140-149.

Keywords

Multiple sclerosis
Optical coherence tomography
Retinal nerve fiber layer
Ganglion cell layer

Authors

Jan Kucharczuk
Zdzisław Maciejek
Bartosz L. Sikorski

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