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Optical coherence tomography in diagnosis and monitoring multiple sclerosis
Affiliations- Department of Ophthalmology, 10th Military Research Hospital with Polyclinic, Bydgoszcz, Poland
- Department of Neurology, 10th Military Research Hospital with Polyclinic, Bydgoszcz, Poland
- Department of Ophthalmology, Nicolaus Copernicus University, Bydgoszcz, Poland
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Abstract
This paper presents application of optical coherence tomography (OCT) for diagnosis and monitoring of multiple sclerosis (MS). The peripapillary retinal nerve fibre layer thinning and the reduced total macular volume analysis are shown. With the course of the MS, the severity of these abnormalities increases which reflects the progressive degeneration of retinal ganglion cells and nerve fibres. The OCT parameters are sensitive, non-invasive indicators useful in assessing the progression of inflammation and neurodegeneration in MS.
Abstract
This paper presents application of optical coherence tomography (OCT) for diagnosis and monitoring of multiple sclerosis (MS). The peripapillary retinal nerve fibre layer thinning and the reduced total macular volume analysis are shown. With the course of the MS, the severity of these abnormalities increases which reflects the progressive degeneration of retinal ganglion cells and nerve fibres. The OCT parameters are sensitive, non-invasive indicators useful in assessing the progression of inflammation and neurodegeneration in MS.
Keywords
Multiple sclerosis, Optical coherence tomography, Retinal nerve fiber layer, Ganglion cell layer
About this articleTitle
Optical coherence tomography in diagnosis and monitoring multiple sclerosis
Journal
Neurologia i Neurochirurgia Polska
Issue
Article type
Review Article
Pages
140-149
Published online
2017-10-31
Page views
311
Article views/downloads
553
DOI
10.1016/j.pjnns.2017.10.009
Bibliographic record
Neurol Neurochir Pol 2018;52(2):140-149.
Keywords
Multiple sclerosis
Optical coherence tomography
Retinal nerve fiber layer
Ganglion cell layer
Authors
Jan Kucharczuk
Zdzisław Maciejek
Bartosz L. Sikorski
