open access

Vol 51, No 5 (2017)
Original research articles
Submitted: 2017-04-11
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Pharmacological stroke prevention in the elderly with atrial fibrillation in Poland – Results of PolSenior study

Beata Łabuz-Roszak, Michał Skrzypek, Agnieszka Machowska-Majchrzak, Małgorzata Mossakowska, Jerzy Chudek, Andrzej Więcek, Krystyna Pierzchała, Beata Łącka-Gaździk, Tomasz Grodzicki
DOI: 10.1016/j.pjnns.2017.07.005
·
Neurol Neurochir Pol 2017;51(5):382-387.

open access

Vol 51, No 5 (2017)
Original research articles
Submitted: 2017-04-11

Abstract

Introduction

Atrial fibrillation (AF) is the most frequent clinically significant arrhythmia, especially common in the elderly. As it is known, AF is associated with increased risk of stroke. Little is known about pharmacological cardiovascular prevention in the elderly with AF in Poland.

Objectives

The purpose of the study was to evaluate the frequency of pharmacological stroke prevention among the elderly with AF in Poland and its association with clinical characteristics and concomitant cardiovascular risk factors.

Patients and methods

The analysis included elderly (≥65 years) participants of the PolSenior study performed in years 2008–2012.

Results

The study group consisted of 4979 people (mean age: 79.3±8.7 years). Among them, there were 875 patients (18.7%) with documented history of AF. Pharmacological prevention with the use of vitamin K antagonists (VKA) was applied by 117 (13.4%) of the elderly with AF, including 15 (1.7%) on dual therapy. Additionally, 386 (45.3%) subjects with AF were using oral antiplatelet therapy (OAPs), mostly aspirin. Acenocoumarol was much more often used than warfarin. New oral anticoagulant drugs (NOACs) were not used at all. Only personal income was associated with the use of VKA. No significant correlation was found for the age, sex, place of residence and level of education.

Conclusions

The study was unique to determine the frequency of pharmacological stroke prevention among elderly people with AF in Poland. It occurred that oral anticoagulant drugs were applied too rarely in this group of patients. Educational programs should be developed among general practitioners concerning current recommendations for patients with AF.

Abstract

Introduction

Atrial fibrillation (AF) is the most frequent clinically significant arrhythmia, especially common in the elderly. As it is known, AF is associated with increased risk of stroke. Little is known about pharmacological cardiovascular prevention in the elderly with AF in Poland.

Objectives

The purpose of the study was to evaluate the frequency of pharmacological stroke prevention among the elderly with AF in Poland and its association with clinical characteristics and concomitant cardiovascular risk factors.

Patients and methods

The analysis included elderly (≥65 years) participants of the PolSenior study performed in years 2008–2012.

Results

The study group consisted of 4979 people (mean age: 79.3±8.7 years). Among them, there were 875 patients (18.7%) with documented history of AF. Pharmacological prevention with the use of vitamin K antagonists (VKA) was applied by 117 (13.4%) of the elderly with AF, including 15 (1.7%) on dual therapy. Additionally, 386 (45.3%) subjects with AF were using oral antiplatelet therapy (OAPs), mostly aspirin. Acenocoumarol was much more often used than warfarin. New oral anticoagulant drugs (NOACs) were not used at all. Only personal income was associated with the use of VKA. No significant correlation was found for the age, sex, place of residence and level of education.

Conclusions

The study was unique to determine the frequency of pharmacological stroke prevention among elderly people with AF in Poland. It occurred that oral anticoagulant drugs were applied too rarely in this group of patients. Educational programs should be developed among general practitioners concerning current recommendations for patients with AF.

Get Citation

Keywords

Atrial fibrillation, Elderly, Direct oral anticoagulant drugs, Oral antiplatelet drugs, Acetylsalicylic acid

About this article
Title

Pharmacological stroke prevention in the elderly with atrial fibrillation in Poland – Results of PolSenior study

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 51, No 5 (2017)

Pages

382-387

DOI

10.1016/j.pjnns.2017.07.005

Bibliographic record

Neurol Neurochir Pol 2017;51(5):382-387.

Keywords

Atrial fibrillation
Elderly
Direct oral anticoagulant drugs
Oral antiplatelet drugs
Acetylsalicylic acid

Authors

Beata Łabuz-Roszak
Michał Skrzypek
Agnieszka Machowska-Majchrzak
Małgorzata Mossakowska
Jerzy Chudek
Andrzej Więcek
Krystyna Pierzchała
Beata Łącka-Gaździk
Tomasz Grodzicki

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