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The effectiveness of Penumbra 400 micro-coils in the embolization of large cerebral aneurysms


- Chair of Radiology, Jagiellonian University Collegium Medicum, Krakow, Poland
- Trauma Center Diagnostic Imaging Unit, University Hospital, Krakow, Poland
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Abstract
The objective of this work is to analyze the effectiveness of Penumbra 400 micro-coils in the embolization of large cerebral aneurysms.
Material and methodsA retrospective analysis has been conducted in a group of 32 patients at the average age of 54.5 years (30–84) for whose embolization the P400 micro-coils (P400) have been used. A control group consisted of 44 patients at the average age of 52.7 years (24–82) in whose aneurysm embolization the 18 micro-coils (MC) have been utilized.
ResultsThe respective percentages of micro-coil packing density in aneurysm sacs were 31.5% for P400 and 29% for MC. The average P400 fluoroscopy time was 21min, and 34min in case of MC. The average number of used micro-coils was 3.9 for P400 and 5.6 for MC. The radiation dose received by a patient was 1.7Gy/2.2Gy, respectively. The recanalization of P400 has occurred in 14/31 cases (45%), and for MC it has occurred in 23/44 (52%) patients. One patient died due to early recanalization after P400 aneurysm embolization.
ConclusionProcedures with use of the P400 demonstrate minimally higher effectiveness of large aneurysms embolization in comparison with the MS with a not much shorter duration and reduction of a radiation dose that a patient receives.
Abstract
The objective of this work is to analyze the effectiveness of Penumbra 400 micro-coils in the embolization of large cerebral aneurysms.
Material and methodsA retrospective analysis has been conducted in a group of 32 patients at the average age of 54.5 years (30–84) for whose embolization the P400 micro-coils (P400) have been used. A control group consisted of 44 patients at the average age of 52.7 years (24–82) in whose aneurysm embolization the 18 micro-coils (MC) have been utilized.
ResultsThe respective percentages of micro-coil packing density in aneurysm sacs were 31.5% for P400 and 29% for MC. The average P400 fluoroscopy time was 21min, and 34min in case of MC. The average number of used micro-coils was 3.9 for P400 and 5.6 for MC. The radiation dose received by a patient was 1.7Gy/2.2Gy, respectively. The recanalization of P400 has occurred in 14/31 cases (45%), and for MC it has occurred in 23/44 (52%) patients. One patient died due to early recanalization after P400 aneurysm embolization.
ConclusionProcedures with use of the P400 demonstrate minimally higher effectiveness of large aneurysms embolization in comparison with the MS with a not much shorter duration and reduction of a radiation dose that a patient receives.
Keywords
Intracranial aneurysm, Embolization, Packing density, Recanalization, Radiation exposure


Title
The effectiveness of Penumbra 400 micro-coils in the embolization of large cerebral aneurysms
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
304-310
Page views
291
Article views/downloads
514
DOI
10.1016/j.pjnns.2017.05.002
Bibliographic record
Neurol Neurochir Pol 2017;51(4):304-310.
Keywords
Intracranial aneurysm
Embolization
Packing density
Recanalization
Radiation exposure
Authors
Tadeusz Jan Popiela
Paweł Brzegowy
Bartłomiej Łasocha
Andrzej Urbanik