open access

Vol 51, No 4 (2017)
Original research articles
Submitted: 2016-07-05
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Early outcomes and periprocedural complications of transarterial embolization of brain arteriovenous malformations with Onyx®

Wojciech Poncyljusz, Marcin Sawicki, Katarzyna Lubkowska, Monika Rać
DOI: 10.1016/j.pjnns.2017.03.006
·
Neurol Neurochir Pol 2017;51(4):277-285.

open access

Vol 51, No 4 (2017)
Original research articles
Submitted: 2016-07-05

Abstract

Background

Brain arteriovenous malformation (BAVM) is a rare pathology diagnosed mostly in young adults. However, due to its hemorrhagic complications, it constitutes an important clinical problem. Treatment modalities available include endovascular, surgery and radiosurgery.

The aim of the study was to assess the efficacy and safety of endovascular treatment of BAVM with Onyx® by reporting one-center experience.

Material and methods

Between 2006 and 2013, 54 patients with BAVM were embolized with Onyx. The group consisted of 24 males and 30 females, aged 10 to 65 years (mean 42.6±15.4). Clinical manifestations of BAVMs were: hemorrhage in 27 (50.0%), headaches in 12 (22.2%), seizures in 7 (13.0%) and focal neurologic deficits in 2 (3.7%) patients. Six (11.1%) patients were asymptomatic. A majority of BAVMs were of II and III grade in Spetzler-Martin scale (19 and 22 cases respectively).

Results

A total number of 108 endovascular procedures were performed (mean 2.00±0.98 sessions/patient). Complete obliteration of malformation was achieved in 25 (46.3%) patients, mostly with grade II and III BAVMs. In 29 (53.7%) patients, embolization led to a decrease in size of BAVM that made it feasible for other treatment modality. Morbidity and mortality rates were 5.6% and 1.8% respectively. The rate of hemorrhagic complications was 9.3%.

Conclusion

Embolization of BAVM with Onyx® is an effective and safe method of treatment. However, regarding type and consequences of complications, the technique needs further improvement.

Abstract

Background

Brain arteriovenous malformation (BAVM) is a rare pathology diagnosed mostly in young adults. However, due to its hemorrhagic complications, it constitutes an important clinical problem. Treatment modalities available include endovascular, surgery and radiosurgery.

The aim of the study was to assess the efficacy and safety of endovascular treatment of BAVM with Onyx® by reporting one-center experience.

Material and methods

Between 2006 and 2013, 54 patients with BAVM were embolized with Onyx. The group consisted of 24 males and 30 females, aged 10 to 65 years (mean 42.6±15.4). Clinical manifestations of BAVMs were: hemorrhage in 27 (50.0%), headaches in 12 (22.2%), seizures in 7 (13.0%) and focal neurologic deficits in 2 (3.7%) patients. Six (11.1%) patients were asymptomatic. A majority of BAVMs were of II and III grade in Spetzler-Martin scale (19 and 22 cases respectively).

Results

A total number of 108 endovascular procedures were performed (mean 2.00±0.98 sessions/patient). Complete obliteration of malformation was achieved in 25 (46.3%) patients, mostly with grade II and III BAVMs. In 29 (53.7%) patients, embolization led to a decrease in size of BAVM that made it feasible for other treatment modality. Morbidity and mortality rates were 5.6% and 1.8% respectively. The rate of hemorrhagic complications was 9.3%.

Conclusion

Embolization of BAVM with Onyx® is an effective and safe method of treatment. However, regarding type and consequences of complications, the technique needs further improvement.

Get Citation

Keywords

Brain arteriovenous malformation, Embolization, Onyx

About this article
Title

Early outcomes and periprocedural complications of transarterial embolization of brain arteriovenous malformations with Onyx®

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 51, No 4 (2017)

Pages

277-285

DOI

10.1016/j.pjnns.2017.03.006

Bibliographic record

Neurol Neurochir Pol 2017;51(4):277-285.

Keywords

Brain arteriovenous malformation
Embolization
Onyx

Authors

Wojciech Poncyljusz
Marcin Sawicki
Katarzyna Lubkowska
Monika Rać

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