open access

Vol 51, No 3 (2017)
Case reports
Submitted: 2017-01-02
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First case of ischemic stroke which happened during continuous intravenous infusion of rt-PA

Anna Zurawska, Jaroslaw Czeczotka, Jacek J. Rozniecki
DOI: 10.1016/j.pjnns.2017.03.001
·
Neurol Neurochir Pol 2017;51(3):263-265.

open access

Vol 51, No 3 (2017)
Case reports
Submitted: 2017-01-02

Abstract

Catheter-directed thrombolysis (CDT) is one of the methods in the treatment of patients with acute lower limb ischemia. It is based on intrathrombus infusion of one of the thrombolytic agents. The most common complication of CDT is bleeding.

We present a patient with left lower limb ischemia, treated by CDT, in which symptoms of stroke, proved to have ischemic etiology, started during continuous intra-arterial infusion of rt-PA. As the patient presented with the history of atrial fibrillation, the most probable mechanism of stroke was related to detachment of possible intra-atrial thrombus. Ischemic stroke which happened during intra-arterial thrombolysis with rt-PA has never been mentioned in literature yet and the case stands for the statement that very effective causative treatment of ischemic stroke with rt-PA is not sufficient to “prevent” ischemic stroke if used in very small doses.

Abstract

Catheter-directed thrombolysis (CDT) is one of the methods in the treatment of patients with acute lower limb ischemia. It is based on intrathrombus infusion of one of the thrombolytic agents. The most common complication of CDT is bleeding.

We present a patient with left lower limb ischemia, treated by CDT, in which symptoms of stroke, proved to have ischemic etiology, started during continuous intra-arterial infusion of rt-PA. As the patient presented with the history of atrial fibrillation, the most probable mechanism of stroke was related to detachment of possible intra-atrial thrombus. Ischemic stroke which happened during intra-arterial thrombolysis with rt-PA has never been mentioned in literature yet and the case stands for the statement that very effective causative treatment of ischemic stroke with rt-PA is not sufficient to “prevent” ischemic stroke if used in very small doses.

Get Citation

Keywords

Stroke, Thrombolysis, Recombinant tissue plasminogen activator, Limb ischemia, Atrial fibrillation

About this article
Title

First case of ischemic stroke which happened during continuous intravenous infusion of rt-PA

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 51, No 3 (2017)

Pages

263-265

DOI

10.1016/j.pjnns.2017.03.001

Bibliographic record

Neurol Neurochir Pol 2017;51(3):263-265.

Keywords

Stroke
Thrombolysis
Recombinant tissue plasminogen activator
Limb ischemia
Atrial fibrillation

Authors

Anna Zurawska
Jaroslaw Czeczotka
Jacek J. Rozniecki

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