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First case of ischemic stroke which happened during continuous intravenous infusion of rt-PA
Affiliations- Barlicki Memorial Hospital, 22 Kopcinskiego Street, 90-153 Lodz, Poland
- Department of Surgery, Medical University of Lodz, 22 Kopcinskiego Street, 90-153 Lodz, Poland
- Department of Neurology, Stroke and Neurorehabilitation, Medical University of Lodz, 22 Kopcinskiego Street, 90-153 Lodz, Poland
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Abstract
Catheter-directed thrombolysis (CDT) is one of the methods in the treatment of patients with acute lower limb ischemia. It is based on intrathrombus infusion of one of the thrombolytic agents. The most common complication of CDT is bleeding.
We present a patient with left lower limb ischemia, treated by CDT, in which symptoms of stroke, proved to have ischemic etiology, started during continuous intra-arterial infusion of rt-PA. As the patient presented with the history of atrial fibrillation, the most probable mechanism of stroke was related to detachment of possible intra-atrial thrombus. Ischemic stroke which happened during intra-arterial thrombolysis with rt-PA has never been mentioned in literature yet and the case stands for the statement that very effective causative treatment of ischemic stroke with rt-PA is not sufficient to “prevent” ischemic stroke if used in very small doses.
Abstract
Catheter-directed thrombolysis (CDT) is one of the methods in the treatment of patients with acute lower limb ischemia. It is based on intrathrombus infusion of one of the thrombolytic agents. The most common complication of CDT is bleeding.
We present a patient with left lower limb ischemia, treated by CDT, in which symptoms of stroke, proved to have ischemic etiology, started during continuous intra-arterial infusion of rt-PA. As the patient presented with the history of atrial fibrillation, the most probable mechanism of stroke was related to detachment of possible intra-atrial thrombus. Ischemic stroke which happened during intra-arterial thrombolysis with rt-PA has never been mentioned in literature yet and the case stands for the statement that very effective causative treatment of ischemic stroke with rt-PA is not sufficient to “prevent” ischemic stroke if used in very small doses.
Keywords
Stroke, Thrombolysis, Recombinant tissue plasminogen activator, Limb ischemia, Atrial fibrillation
About this articleTitle
First case of ischemic stroke which happened during continuous intravenous infusion of rt-PA
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
263-265
Page views
277
Article views/downloads
353
DOI
10.1016/j.pjnns.2017.03.001
Bibliographic record
Neurol Neurochir Pol 2017;51(3):263-265.
Keywords
Stroke
Thrombolysis
Recombinant tissue plasminogen activator
Limb ischemia
Atrial fibrillation
Authors
Anna Zurawska
Jaroslaw Czeczotka
Jacek J. Rozniecki
