Błąd cURL: Failed connect to www.viamedica.pl:443; No route to host
Vol 50, No 6 (2016)

open access

Page views 489
Article views/downloads 553
Get Citation

Connect on Social Media

Connect on Social Media

Endoscopic transsphenoidal surgery using pedicle vascularized nasoseptal flap for cholesterol granuloma in petrous apex: A technical note

Yukitomo Ishi1, Hiroyuki Kobayashi1, Hiroaki Motegi1, Shogo Endo1, Shigeru Yamaguchi1, Shunsuke Terasaka1, Kiyohiro Houkin1
DOI: 10.1016/j.pjnns.2016.08.006
Neurol Neurochir Pol 2016;50(6):504-510.



Compared with surgical resection, endoscopic transsphenoidal surgery (TSS) for cholesterol granuloma (CG) in the petrous apex (PA) is associated with local recurrence due to obstruction of the drainage route. We present a detailed procedure of an endoscopic TSS using pedicle vascularized nasoseptal flap (PVNF).


A 40-year-old woman with a history of repeated surgery for left tympanitis was referred to our institution. Neurological examination revealed severe hearing loss in the left ear. Radiologic examination presented a round mass in the left PA and significant fluid collection in the mastoid air cells of the left temporal bone. CG was strongly suspected, and endoscopic TSS using PVNF was performed. Prior to endoscopic drainage, a PVNF was harvested from the mucosa of the ipsilateral nasal septum, with an attempt to preserve the sphenopalatine artery in the flap. Following this, puncture and adequate irrigation of the lesion was performed by endoscopic TSS, with neuro-navigation system assistance; the apex of PVNF was then placed into the lesion to prevent the obstruction of the drainage route. An absorbable polyglycolic acid sheet and fibrin glue were applied on the flap to prevent spontaneous deviation from the lesion.


The patient was discharged without any further neurological complications. Eight-month postoperative computed tomography images showed no recurrence; the drainage route was patent and the fluid collection in the left mastoid air cells was resolved. Moreover, hearing loss was improved.


Endoscopic TSS using PVNF may be one of available surgical options for PACG.

Article available in PDF format

View PDF Download PDF file
Błąd cURL: Failed connect to www.viamedica.pl:443; No route to host

Neurologia i Neurochirurgia Polska