open access

Vol 50, No 6 (2016)
Original research articles
Submitted: 2016-03-31
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Suicidality and its determinants among Polish patients with epilepsy

Magdalena Bosak, Wojciech Turaj, Dominika Dudek, Marcin Siwek, Andrzej Szczudlik
DOI: 10.1016/j.pjnns.2016.07.009
·
Neurol Neurochir Pol 2016;50(6):432-438.

open access

Vol 50, No 6 (2016)
Original research articles
Submitted: 2016-03-31

Abstract

Background and purpose

The aim of this study was to evaluate the prevalence of suicidal ideation among Polish patients with epilepsy and to assess the potential determinants of suicidality in this cohort.

Material and methods

The study comprised 301 patients with epilepsy seen in the tertiary epilepsy clinic. Patients’ characteristics included demographic variables, epilepsy-related variables, as well as occurrence of comorbidities, ongoing use of any other medications, family history of epilepsy and/or depression. Beck Depression Inventory (BDI) was used to assess depressive symptoms, and question no. 9 of BDI was specifically used to reveal suicidality.

Results

Mean age of subjects was 35.5 years. 113 (37.5%) had frequent seizures and 96 patients (31.9%) had remission. BDI score>11 points (suggestive for depression) was found in 127 subjects. Suicidal ideation has been revealed in 30 (10.0%) out of 301 studied patients. Patients with suicidal ideation were older and more commonly reported frequent seizures. Almost all of them (93.3%) had clinically significant depressive symptoms (BDI score>11). Multivariate analysis revealed that severity of depressive symptoms (OR=1.16 per one-point increase in BDI score, 95% CI: 1.10–1.22, p<0.001) and the use of potentially depressogenic medication (OR=3.04, 95% CI: 1.04–8.89, p=0.04) were independent determinants of suicidality among studied patients.

Conclusions

Suicidal ideations were revealed by about 10% of studied epileptic patients who visited tertiary center for epilepsy. Independent predictors of suicidality among studied patients included depression itself and the use of potentially depressogenic medication.

Abstract

Background and purpose

The aim of this study was to evaluate the prevalence of suicidal ideation among Polish patients with epilepsy and to assess the potential determinants of suicidality in this cohort.

Material and methods

The study comprised 301 patients with epilepsy seen in the tertiary epilepsy clinic. Patients’ characteristics included demographic variables, epilepsy-related variables, as well as occurrence of comorbidities, ongoing use of any other medications, family history of epilepsy and/or depression. Beck Depression Inventory (BDI) was used to assess depressive symptoms, and question no. 9 of BDI was specifically used to reveal suicidality.

Results

Mean age of subjects was 35.5 years. 113 (37.5%) had frequent seizures and 96 patients (31.9%) had remission. BDI score>11 points (suggestive for depression) was found in 127 subjects. Suicidal ideation has been revealed in 30 (10.0%) out of 301 studied patients. Patients with suicidal ideation were older and more commonly reported frequent seizures. Almost all of them (93.3%) had clinically significant depressive symptoms (BDI score>11). Multivariate analysis revealed that severity of depressive symptoms (OR=1.16 per one-point increase in BDI score, 95% CI: 1.10–1.22, p<0.001) and the use of potentially depressogenic medication (OR=3.04, 95% CI: 1.04–8.89, p=0.04) were independent determinants of suicidality among studied patients.

Conclusions

Suicidal ideations were revealed by about 10% of studied epileptic patients who visited tertiary center for epilepsy. Independent predictors of suicidality among studied patients included depression itself and the use of potentially depressogenic medication.

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Keywords

Epilepsy, Suicidality, Depression, Seizures, Risk factors

About this article
Title

Suicidality and its determinants among Polish patients with epilepsy

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 50, No 6 (2016)

Pages

432-438

DOI

10.1016/j.pjnns.2016.07.009

Bibliographic record

Neurol Neurochir Pol 2016;50(6):432-438.

Keywords

Epilepsy
Suicidality
Depression
Seizures
Risk factors

Authors

Magdalena Bosak
Wojciech Turaj
Dominika Dudek
Marcin Siwek
Andrzej Szczudlik

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