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Improvement of quality of life after therapeutic plasma exchange in patients with myasthenic crisis
Affiliations- Department of Neurology in Zabrze, Medical University of Silesia in Katowice with the Division of Dentistry in Zabrze
- Department of Anesthesiology and Intensive Therapy, Medical University of Silesia, Katowice, Poland, Department of Anesthesiology and Intensive Therapy, Medical University of Silesia, 3 Maja 13-15,, 41-800 Zabrze, Poland
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Abstract
We sought to evaluate quality of life patients with myasthenic crisis before and after therapeutic plasma exchange.
Materials and methodsIn our study we conducted an assessment of the quality of life with the use of the questionnaire SF-36, when executed eleven therapeutic plasma exchange. The assessment was made on baseline and after 4 weeks. We also did neurological clinical evaluation before and after TPE.
ResultsPatients in the study showed significant improvement in quality of life after performed therapeutic plasma exchange. The changes were observed in physical functioning, which confirmed the results of the statistical significance of p<0.05. In the analysis, the assessment of mental functioning not obtained the results of statistical significance, but the results also showed improvement in self-assessment. We observed high correlation between general health and physical mental functioning, between the role limitations due to physical health problems and role limitations due to emotional problems, and general health perception and bodily pain.
ConclusionsTherapeutic plasma exchange significantly improves the quality of life of patients with myasthenia gravis during the crisis.
Abstract
We sought to evaluate quality of life patients with myasthenic crisis before and after therapeutic plasma exchange.
Materials and methodsIn our study we conducted an assessment of the quality of life with the use of the questionnaire SF-36, when executed eleven therapeutic plasma exchange. The assessment was made on baseline and after 4 weeks. We also did neurological clinical evaluation before and after TPE.
ResultsPatients in the study showed significant improvement in quality of life after performed therapeutic plasma exchange. The changes were observed in physical functioning, which confirmed the results of the statistical significance of p<0.05. In the analysis, the assessment of mental functioning not obtained the results of statistical significance, but the results also showed improvement in self-assessment. We observed high correlation between general health and physical mental functioning, between the role limitations due to physical health problems and role limitations due to emotional problems, and general health perception and bodily pain.
ConclusionsTherapeutic plasma exchange significantly improves the quality of life of patients with myasthenia gravis during the crisis.
Keywords
Myasthenia gravis, Therapeutic plasma exchange, Plasmapheresis, Quality of life, Questionnaire SF-36
About this articleTitle
Improvement of quality of life after therapeutic plasma exchange in patients with myasthenic crisis
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
418-424
Page views
348
Article views/downloads
741
DOI
10.1016/j.pjnns.2016.07.005
Bibliographic record
Neurol Neurochir Pol 2016;50(6):418-424.
Keywords
Myasthenia gravis
Therapeutic plasma exchange
Plasmapheresis
Quality of life
Questionnaire SF-36
Authors
Izabela Rozmilowska
Monika Adamczyk-Sowa
Katarzyna Rutkowska
Krystyna Pierzchala
Hanna Misiolek
