Vol 50, No 6 (2016)

open access

Page views 356
Article views/downloads 753
Get Citation

Connect on Social Media

Connect on Social Media

Improvement of quality of life after therapeutic plasma exchange in patients with myasthenic crisis

Izabela Rozmilowska1, Monika Adamczyk-Sowa1, Katarzyna Rutkowska2, Krystyna Pierzchala1, Hanna Misiolek2
DOI: 10.1016/j.pjnns.2016.07.005
Neurol Neurochir Pol 2016;50(6):418-424.



We sought to evaluate quality of life patients with myasthenic crisis before and after therapeutic plasma exchange.

Materials and methods

In our study we conducted an assessment of the quality of life with the use of the questionnaire SF-36, when executed eleven therapeutic plasma exchange. The assessment was made on baseline and after 4 weeks. We also did neurological clinical evaluation before and after TPE.


Patients in the study showed significant improvement in quality of life after performed therapeutic plasma exchange. The changes were observed in physical functioning, which confirmed the results of the statistical significance of p<0.05. In the analysis, the assessment of mental functioning not obtained the results of statistical significance, but the results also showed improvement in self-assessment. We observed high correlation between general health and physical mental functioning, between the role limitations due to physical health problems and role limitations due to emotional problems, and general health perception and bodily pain.


Therapeutic plasma exchange significantly improves the quality of life of patients with myasthenia gravis during the crisis.

Article available in PDF format

View PDF Download PDF file

Neurologia i Neurochirurgia Polska