open access

Vol 50, No 4 (2016)
Case reports
Submitted: 2016-01-31
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Intravascular lymphoma mimicking multiple sclerosis

Grzegorz Kloc, Małgorzata Budziak, Agnieszka Więckiewicz, Mateusz Pleśniak, Halina Bartosik-Psujek
DOI: 10.1016/j.pjnns.2016.04.007
·
Neurol Neurochir Pol 2016;50(4):313-317.

open access

Vol 50, No 4 (2016)
Case reports
Submitted: 2016-01-31

Abstract

Diagnosis of relapsing–remitting multiple sclerosis requires demonstration disseminated symptoms in time and space on the basis of neurological assessment or magnetic resonance imaging findings. In addition, the diagnosis is conditioned by ruling out other conditions that may explain the clinical symptoms.

We describe the patient presenting in the initial stage of the disease neurological symptoms and magnetic resonance imaging lesions, that met criteria for relapsing–remitting multiple sclerosis diagnosis.

The patient was administered immunomodulatory treatment. However, the subsequent course of the disease tended to verify the diagnosis. Finally, the patient was diagnosed with intravascular B-cell lymphoma.

Intravascular lymphoma is a rare form of lymphoma characterized by the development of cancerous cells in the lumen of small and medium-sized blood vessels.

Due to the lack of characteristic biomarkers in laboratory tests and neuroimaging, the diagnosis is based on histopathological examination of the sample of the affected organ taken by biopsy. It should be consider in all cases of central nervous system damage of unknown, undiagnosed etiology.

Abstract

Diagnosis of relapsing–remitting multiple sclerosis requires demonstration disseminated symptoms in time and space on the basis of neurological assessment or magnetic resonance imaging findings. In addition, the diagnosis is conditioned by ruling out other conditions that may explain the clinical symptoms.

We describe the patient presenting in the initial stage of the disease neurological symptoms and magnetic resonance imaging lesions, that met criteria for relapsing–remitting multiple sclerosis diagnosis.

The patient was administered immunomodulatory treatment. However, the subsequent course of the disease tended to verify the diagnosis. Finally, the patient was diagnosed with intravascular B-cell lymphoma.

Intravascular lymphoma is a rare form of lymphoma characterized by the development of cancerous cells in the lumen of small and medium-sized blood vessels.

Due to the lack of characteristic biomarkers in laboratory tests and neuroimaging, the diagnosis is based on histopathological examination of the sample of the affected organ taken by biopsy. It should be consider in all cases of central nervous system damage of unknown, undiagnosed etiology.

Get Citation

Keywords

MRI, RIS, CSF, MS, RR–MS, CT, IVL, CNS

About this article
Title

Intravascular lymphoma mimicking multiple sclerosis

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 50, No 4 (2016)

Pages

313-317

DOI

10.1016/j.pjnns.2016.04.007

Bibliographic record

Neurol Neurochir Pol 2016;50(4):313-317.

Keywords

MRI
RIS
CSF
MS
RR–MS
CT
IVL
CNS

Authors

Grzegorz Kloc
Małgorzata Budziak
Agnieszka Więckiewicz
Mateusz Pleśniak
Halina Bartosik-Psujek

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