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Association of myasthenia gravis and Behçet's disease: A case report
Affiliations- Department of Neurology, Celal Bayar University, Manisa, Türkiye
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Abstract
Myasthenia gravis is a disease of neuromuscular junction due to auto-immune destruction of the acetylcholine receptors. Behçet's disease, on the other hand, is a multisystemic vascular-inflammatory disease. Both conditions are not common in the general population although their association has not been reported in the literature. We wanted to present our patient who developed clinical course of myasthenia gravis following discontinuation of medications due to complications of corticosteroid for Behçet's disease. It was observed that clinical findings of myasthenia gravis recovered following restarting steroid treatment and he did not experience attacks of both conditions. Although Myasthenia gravis and Behçet's disease are distinct entities clinically as well as in terms of pathogenesis, they share common physiopathological features and their treatment is based on their common features.
Abstract
Myasthenia gravis is a disease of neuromuscular junction due to auto-immune destruction of the acetylcholine receptors. Behçet's disease, on the other hand, is a multisystemic vascular-inflammatory disease. Both conditions are not common in the general population although their association has not been reported in the literature. We wanted to present our patient who developed clinical course of myasthenia gravis following discontinuation of medications due to complications of corticosteroid for Behçet's disease. It was observed that clinical findings of myasthenia gravis recovered following restarting steroid treatment and he did not experience attacks of both conditions. Although Myasthenia gravis and Behçet's disease are distinct entities clinically as well as in terms of pathogenesis, they share common physiopathological features and their treatment is based on their common features.
Keywords
Behçet' s disease, Myasthenia gravis, Autoimmune, Acetylcholine receptor antibody, Corticosteroid
About this articleTitle
Association of myasthenia gravis and Behçet's disease: A case report
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
284-287
Page views
296
Article views/downloads
447
DOI
10.1016/j.pjnns.2016.03.007
Bibliographic record
Neurol Neurochir Pol 2016;50(4):284-287.
Keywords
Behçet's disease
Myasthenia gravis
Autoimmune
Acetylcholine receptor antibody
Corticosteroid
Authors
Aysin Kisabay
Ummu Serpil Sari
Recep Boyaci
Melike Batum
Hikmet Yilmaz
Deniz Selcuki
