open access

Vol 50, No 4 (2016)
Case reports
Submitted: 2016-01-28
Get Citation

Cortical laminar necrosis following myocardial infarction

Simona Lattanzi, Mauro Silvestrini, Leandro Provinciali
DOI: 10.1016/j.pjnns.2016.03.001
·
Neurol Neurochir Pol 2016;50(4):271-274.

open access

Vol 50, No 4 (2016)
Case reports
Submitted: 2016-01-28

Abstract

The cortical laminar necrosis (CLN) is a permanent injury characterized by the selective delayed necrosis of the cerebral cortex, mainly of the third layer, and usually greater in the depths and sides of the sulci than over the crest of the gyri. The damage involves all cellular components – either neurons, glia cells and blood vessels – and results in a focal cortical band of pan-necrosis detectable in late sub-acute or chronic stages of reduced energy supply to the brain. The CLN has been described in different conditions as hypoxia, hypoglycemia and status epilepticus. At brain CT or MR scans it appears with pathognomonic highly hyperdense or T1-hyperintense lesions following the gyral anatomy of the cerebral cortex. We reported a case of CLN associated to myocardial infarct and discussed the underlying mechanisms.

Abstract

The cortical laminar necrosis (CLN) is a permanent injury characterized by the selective delayed necrosis of the cerebral cortex, mainly of the third layer, and usually greater in the depths and sides of the sulci than over the crest of the gyri. The damage involves all cellular components – either neurons, glia cells and blood vessels – and results in a focal cortical band of pan-necrosis detectable in late sub-acute or chronic stages of reduced energy supply to the brain. The CLN has been described in different conditions as hypoxia, hypoglycemia and status epilepticus. At brain CT or MR scans it appears with pathognomonic highly hyperdense or T1-hyperintense lesions following the gyral anatomy of the cerebral cortex. We reported a case of CLN associated to myocardial infarct and discussed the underlying mechanisms.

Get Citation

Keywords

Stroke, Cerebrovascular disease, Clinical neurology

About this article
Title

Cortical laminar necrosis following myocardial infarction

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 50, No 4 (2016)

Pages

271-274

DOI

10.1016/j.pjnns.2016.03.001

Bibliographic record

Neurol Neurochir Pol 2016;50(4):271-274.

Keywords

Stroke
Cerebrovascular disease
Clinical neurology

Authors

Simona Lattanzi
Mauro Silvestrini
Leandro Provinciali

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: viamedica@viamedica.pl