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A challenging entity of unruptured giant saccular aneurysms of vertebrobasilar artery
Affiliations- Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Beijing Engineering Research Center for Interventional Neuroradiology, Capital Medical University, Beijing
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Abstract
Giant intracranial aneurysms commonly cause poor clinical outcome and few studies focus on them. This study is to retrospectively report the angiographic and clinical presentations in unruptured giant saccular vertebrobasilar aneurysms with and without endovascular treatment.
MethodsOut of 400 patients who had unruptured posterior circulation aneurysms in a single center, we found 10 unruptured giant (>25mm) saccular vertebrobasilar aneurysms. Clinical and angiographic presentations as well as their clinical outcomes were assessed.
ResultsOf the 10 giant aneurysms in 10 patients, three were left untreated. During 6 months follow-up, all 3 of these patients died from aneurysm rupture. The remaining 7 patients were treated by endovascular procedure, 5 received stent-assisted coiling, 1 was treated by parent artery occlusion (PAO), and 1 was treated by conventional coiling. Of these treated patients, only one survived during a 22 month period of follow-up.
ConclusionsPatients with giant saccular aneurysms of vertebrobasilar artery presenting mass effect may have extremely poor clinical outcomes and may not benefit from endovascular treatment.
Abstract
Giant intracranial aneurysms commonly cause poor clinical outcome and few studies focus on them. This study is to retrospectively report the angiographic and clinical presentations in unruptured giant saccular vertebrobasilar aneurysms with and without endovascular treatment.
MethodsOut of 400 patients who had unruptured posterior circulation aneurysms in a single center, we found 10 unruptured giant (>25mm) saccular vertebrobasilar aneurysms. Clinical and angiographic presentations as well as their clinical outcomes were assessed.
ResultsOf the 10 giant aneurysms in 10 patients, three were left untreated. During 6 months follow-up, all 3 of these patients died from aneurysm rupture. The remaining 7 patients were treated by endovascular procedure, 5 received stent-assisted coiling, 1 was treated by parent artery occlusion (PAO), and 1 was treated by conventional coiling. Of these treated patients, only one survived during a 22 month period of follow-up.
ConclusionsPatients with giant saccular aneurysms of vertebrobasilar artery presenting mass effect may have extremely poor clinical outcomes and may not benefit from endovascular treatment.
Keywords
Unruptured aneurysms, Giant saccular aneurysms, Vertebrobasilar artery, Endovascular treatment, Clinical outcomes
About this articleTitle
A challenging entity of unruptured giant saccular aneurysms of vertebrobasilar artery
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
236-240
Page views
261
Article views/downloads
308
DOI
10.1016/j.pjnns.2016.04.001
Bibliographic record
Neurol Neurochir Pol 2016;50(4):236-240.
Keywords
Unruptured aneurysms
Giant saccular aneurysms
Vertebrobasilar artery
Endovascular treatment
Clinical outcomes
Authors
Huijian Ge
Youxiang Li
Xianli Lv
