open access
Mild Cognitive Impairment as a single sign of brain hemiatrophy in patient with Localized Scleroderma and Parry–Romberg Syndrome
Affiliations- Department of Neurology, University Hospital no. 2, Bydgoszcz, Poland
- Department of Neurology, Jagiellonian University, School of Medicine, Krakow, Poland
open access
Abstract
Neurologic involvement is well recognized in Systemic Scleroderma and increasingly reported in Localized Scleroderma. MRI brain abnormalities are often associated with symptoms such as seizures or headaches. In some cases they may be clinically silent. We describe a 23 years old female with head, trunk and limbs scleroderma who developed Parry–Romberg Syndrome. Brain MRI showed ipsilateral temporal lobe atrophy without any prominent neurologic symptoms. Neuropsychological examination revealed Mild Cognitive Impairment. During the 7 years of follow up we have noticed progression of face atrophy but no progression of brain atrophy. Cognitive functions have been stable. This case highlight that major MRI brain abnormalities in LS may occur with only subtle clinical manifestation such as Mild Cognitive Impairment.
Abstract
Neurologic involvement is well recognized in Systemic Scleroderma and increasingly reported in Localized Scleroderma. MRI brain abnormalities are often associated with symptoms such as seizures or headaches. In some cases they may be clinically silent. We describe a 23 years old female with head, trunk and limbs scleroderma who developed Parry–Romberg Syndrome. Brain MRI showed ipsilateral temporal lobe atrophy without any prominent neurologic symptoms. Neuropsychological examination revealed Mild Cognitive Impairment. During the 7 years of follow up we have noticed progression of face atrophy but no progression of brain atrophy. Cognitive functions have been stable. This case highlight that major MRI brain abnormalities in LS may occur with only subtle clinical manifestation such as Mild Cognitive Impairment.
Keywords
Localized Scleroderma, Facial hemiatrophy, Parry–Romberg Syndrome, Neurocutaneous Syndrome, Mild Cognitive Impairment, Magnetic Resonance Imaging
About this articleTitle
Mild Cognitive Impairment as a single sign of brain hemiatrophy in patient with Localized Scleroderma and Parry–Romberg Syndrome
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
215-218
Page views
316
Article views/downloads
1132
DOI
10.1016/j.pjnns.2016.02.002
Bibliographic record
Neurol Neurochir Pol 2016;50(3):215-218.
Keywords
Localized Scleroderma
Facial hemiatrophy
Parry–Romberg Syndrome
Neurocutaneous Syndrome
Mild Cognitive Impairment
Magnetic Resonance Imaging
Authors
Elzbieta Klimiec
Aleksandra Klimkowicz-Mrowiec
