open access

Vol 50, No 3 (2016)
Case reports
Submitted: 2015-12-02
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Medulloblastoma with suprasellar solitary massive metastasis: Case report

Hiroaki Nagashima, Tatsuya Nagashima, Atsufumi Kawamura, Kazuki Yamamoto, Makiko Yoshida, Daiichiro Hasegawa, Yoshiyuki Kosaka, Eiji Kohmura
DOI: 10.1016/j.pjnns.2016.02.001
·
Neurol Neurochir Pol 2016;50(3):211-214.

open access

Vol 50, No 3 (2016)
Case reports
Submitted: 2015-12-02

Abstract

It is extremely rare for metastasised medulloblastoma to form a large tumour in the suprasellar region. We present a case of medulloblastoma with large suprasellar metastasis at initial presentation. A 3-year and 5-month-old boy presented with a 1-month history of vomiting and loss of appetite, and body weight. Computed tomography and magnetic resonance imaging revealed a 20mm×20mm mass in the suprasellar region and a 30mm×30mm mass in the fourth cerebral ventricle. We performed endoscopic biopsy of the suprasellar tumour, and subsequently totally removed the vermian tumour through a suboccipital craniotomy. The histopathological findings revealed that both the suprasellar and vermian tumours were classic type and non SHH/WNT type medulloblastoma. The postoperative course was uneventful. The patient showed complete remission after chemotherapy. The tumour in the suprasellar region was most likely metastatic from the vermis. Endoscopic biopsy of the tumour in the suprasellar region and total removal of the tumour in the vermis in a one-stage operation followed by intensive chemotherapy with reduced dose radiotherapy may provide a satisfactory outcome.

Abstract

It is extremely rare for metastasised medulloblastoma to form a large tumour in the suprasellar region. We present a case of medulloblastoma with large suprasellar metastasis at initial presentation. A 3-year and 5-month-old boy presented with a 1-month history of vomiting and loss of appetite, and body weight. Computed tomography and magnetic resonance imaging revealed a 20mm×20mm mass in the suprasellar region and a 30mm×30mm mass in the fourth cerebral ventricle. We performed endoscopic biopsy of the suprasellar tumour, and subsequently totally removed the vermian tumour through a suboccipital craniotomy. The histopathological findings revealed that both the suprasellar and vermian tumours were classic type and non SHH/WNT type medulloblastoma. The postoperative course was uneventful. The patient showed complete remission after chemotherapy. The tumour in the suprasellar region was most likely metastatic from the vermis. Endoscopic biopsy of the tumour in the suprasellar region and total removal of the tumour in the vermis in a one-stage operation followed by intensive chemotherapy with reduced dose radiotherapy may provide a satisfactory outcome.

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Keywords

Medulloblastoma, Metastasis, Suprasellar region

About this article
Title

Medulloblastoma with suprasellar solitary massive metastasis: Case report

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 50, No 3 (2016)

Pages

211-214

DOI

10.1016/j.pjnns.2016.02.001

Bibliographic record

Neurol Neurochir Pol 2016;50(3):211-214.

Keywords

Medulloblastoma
Metastasis
Suprasellar region

Authors

Hiroaki Nagashima
Tatsuya Nagashima
Atsufumi Kawamura
Kazuki Yamamoto
Makiko Yoshida
Daiichiro Hasegawa
Yoshiyuki Kosaka
Eiji Kohmura

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