open access
Unilateral progressive muscular atrophy with fast symptoms progression
open access
Abstract
Progressive muscular atrophy (PMA), or the lower motor neuron disease, is a sporadic disorder characterized by onset in adulthood, pure lower motor neuron involvement and relatively benign course. Muscle atrophy and weakness may be symmetrical or asymmetrical, but they are always bilateral. We present a male patient with exclusively left-side flaccid paresis due to lower motor neuron disease without electromyographic evidence of neurogenic lesion of contralateral muscles and with no signs of corticospinal tracts involvement. The rapid disease progression was typical of the generalized phenotype of PMA and it suggested the relation to the aggressive course of classical ALS.
Abstract
Progressive muscular atrophy (PMA), or the lower motor neuron disease, is a sporadic disorder characterized by onset in adulthood, pure lower motor neuron involvement and relatively benign course. Muscle atrophy and weakness may be symmetrical or asymmetrical, but they are always bilateral. We present a male patient with exclusively left-side flaccid paresis due to lower motor neuron disease without electromyographic evidence of neurogenic lesion of contralateral muscles and with no signs of corticospinal tracts involvement. The rapid disease progression was typical of the generalized phenotype of PMA and it suggested the relation to the aggressive course of classical ALS.
Keywords
Motor neuron disease, Progressive muscular atrophy, Unilateral symptoms, Electromyography
About this articleTitle
Unilateral progressive muscular atrophy with fast symptoms progression
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
52-54
DOI
10.1016/j.pjnns.2015.10.009
Bibliographic record
Neurol Neurochir Pol 2016;50(1):52-54.
Keywords
Motor neuron disease
Progressive muscular atrophy
Unilateral symptoms
Electromyography
Authors
Andrzej Bogucki
Justyna Pigońska
Iwona Szadkowska
Agata Gajos