Vol 49, No 6 (2015)

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Malignant transformation of diffuse infiltrating glial neoplasm after prolonged stable period initially discovered with hypothalamic hamartoma

Fumiaki Ueda1, Hiroyuki Aburano2, Yuichi Yoshie2, Osamu Matsui1, Toshifumi Gabata2
DOI: 10.1016/j.pjnns.2015.08.003
Neurol Neurochir Pol 2015;49(6):441-445.

Abstract

We present a case of malignant transformation of diffuse infiltrating glial neoplasm after a prolonged stable period on magnetic resonance imaging (MRI) and spectroscopy (MRS) initially discovered with a hypothalamic hamartoma. Although MRI and MRS suggest the possibility of malignant transformation in future, they cannot precisely predict the timing of rapid growth.

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