open access

Vol 49, No 6 (2015)
Original research articles
Submitted: 2015-06-08
Get Citation

Auditory spatial deficits in brainstem disorders

Tomasz Przewoźny, Anna Gójska-Grymajło, Tomasz Szmuda, Karolina Markiet
DOI: 10.1016/j.pjnns.2015.10.001
·
Neurol Neurochir Pol 2015;49(6):401-411.

open access

Vol 49, No 6 (2015)
Original research articles
Submitted: 2015-06-08

Abstract

Purpose

Brainstem disorders seem to negatively influence the central auditory system, causing spatial hearing deficits.

Material and methods

We tested 11 patients with brainstem lesions due to ischemic stroke (IS), multiple sclerosis (MS), or cerebellopontine angle tumor (CPAT) together with 50 age- and sex-matched healthy volunteers. We used pure tone audiometry (PTAud), brainstem auditory evoked potentials (BAEPs) and the horizontal minimum audible angle test (HMAAT) for 8 azimuths with binaural stimulation.

Results

The chosen patients and the controls had normal or near normal hearing in PTAud. BAEPs interaural wave I–V latency difference was over 7 times longer in the patients group compared to the controls. Additionally, 9 of the 11 patients (81.1%) had abnormal HMAAT results. The biggest quantitative disturbances in HMAAT were present in the CPAT and the MS patients. The sound localization ability in HMAAT was significantly worse in the patients in 0° azimuth in comparison with the controls, and in 45° and 90° azimuth in patients with auditory pathway involvement compared with the ones without the involvement.

Conclusions

Our study confirms the strong relationship between various brainstem pathologies and sound localization disability and sheds some light on the complexity of the relationship.

Abstract

Purpose

Brainstem disorders seem to negatively influence the central auditory system, causing spatial hearing deficits.

Material and methods

We tested 11 patients with brainstem lesions due to ischemic stroke (IS), multiple sclerosis (MS), or cerebellopontine angle tumor (CPAT) together with 50 age- and sex-matched healthy volunteers. We used pure tone audiometry (PTAud), brainstem auditory evoked potentials (BAEPs) and the horizontal minimum audible angle test (HMAAT) for 8 azimuths with binaural stimulation.

Results

The chosen patients and the controls had normal or near normal hearing in PTAud. BAEPs interaural wave I–V latency difference was over 7 times longer in the patients group compared to the controls. Additionally, 9 of the 11 patients (81.1%) had abnormal HMAAT results. The biggest quantitative disturbances in HMAAT were present in the CPAT and the MS patients. The sound localization ability in HMAAT was significantly worse in the patients in 0° azimuth in comparison with the controls, and in 45° and 90° azimuth in patients with auditory pathway involvement compared with the ones without the involvement.

Conclusions

Our study confirms the strong relationship between various brainstem pathologies and sound localization disability and sheds some light on the complexity of the relationship.

Get Citation

Keywords

SPL, HL, HMAAT, BAEPs, PTA, PTAud, kHz, dB, ITD, IID, HRTFs, IS, CPAT, MS, FDA, DCN, VAS, TB, SOC, LL, IC

About this article
Title

Auditory spatial deficits in brainstem disorders

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 49, No 6 (2015)

Pages

401-411

DOI

10.1016/j.pjnns.2015.10.001

Bibliographic record

Neurol Neurochir Pol 2015;49(6):401-411.

Keywords

SPL
HL
HMAAT
BAEPs
PTA
PTAud
kHz
dB
ITD
IID
HRTFs
IS
CPAT
MS
FDA
DCN
VAS
TB
SOC
LL
IC

Authors

Tomasz Przewoźny
Anna Gójska-Grymajło
Tomasz Szmuda
Karolina Markiet

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