open access

Vol 49, No 5 (2015)
Review article
Submitted: 2015-06-23
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Potential role of statins in the intracerebral hemorrhage and subarachnoid hemorrhage

Dariusz Kotlęga, Monika Gołąb-Janowska, Marta Masztalewicz, Sylwester Ciećwież, Przemysław Nowacki
DOI: 10.1016/j.pjnns.2015.07.007
·
Neurol Neurochir Pol 2015;49(5):322-328.

open access

Vol 49, No 5 (2015)
Review article
Submitted: 2015-06-23

Abstract

Statins are used in primary and secondary prevention of cardiovascular episodes. Most of recent studies regard ischemic stroke. There are more emerging results of studies suggesting usefulness of these drugs in the other types of stroke e.g. intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH). Searching for new methods of treatment is important, because both ICH and SAH lead to poor prognosis and severe psychomotor disability.

The unquestionable role of inflammatory factors in the pathogenesis of these disorders justifies considering statin treatment. Previous results are contradictory, thus in present study we review results of studies and try to explain the potential pathomechanism of statin use in hemorrhagic strokes.

Abstract

Statins are used in primary and secondary prevention of cardiovascular episodes. Most of recent studies regard ischemic stroke. There are more emerging results of studies suggesting usefulness of these drugs in the other types of stroke e.g. intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH). Searching for new methods of treatment is important, because both ICH and SAH lead to poor prognosis and severe psychomotor disability.

The unquestionable role of inflammatory factors in the pathogenesis of these disorders justifies considering statin treatment. Previous results are contradictory, thus in present study we review results of studies and try to explain the potential pathomechanism of statin use in hemorrhagic strokes.

Get Citation

Keywords

Statins, Intracerebral hemorrhage, Subarachnoid hemorrhage, Inflammation

About this article
Title

Potential role of statins in the intracerebral hemorrhage and subarachnoid hemorrhage

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 49, No 5 (2015)

Pages

322-328

DOI

10.1016/j.pjnns.2015.07.007

Bibliographic record

Neurol Neurochir Pol 2015;49(5):322-328.

Keywords

Statins
Intracerebral hemorrhage
Subarachnoid hemorrhage
Inflammation

Authors

Dariusz Kotlęga
Monika Gołąb-Janowska
Marta Masztalewicz
Sylwester Ciećwież
Przemysław Nowacki

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