open access

Vol 49, No 2 (2015)
Case reports
Submitted: 2018-10-24
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Progressive subacute Miller-Fisher syndrome successfully treated with plasmapheresis

Maria Ejma, Marta Waliszewska-Prosół, Anna Hofman, Sławomir Budrewicz, Ryszard Podemski, Małgorzata Bilińska, Magdalena Koszewicz
DOI: 10.1016/j.pjnns.2015.03.002
·
Neurol Neurochir Pol 2015;49(2):137-138.

open access

Vol 49, No 2 (2015)
Case reports
Submitted: 2018-10-24

Abstract

Background

Miller-Fisher Syndrome (MFS) is a rare acute polyneuropathy composed of the clinical triad of ataxia, areflexia and ophthalmoplegia, with a monophasic, self-limited course and spontaneous improvement.

Case report

The authors present a 65-year-old man with Miller-Fisher syndrome consisting of bilateral ophthalmoplegia, trigeminal and facial nerve palsy, mild ataxia and peripheral neuropathy. The disease had a progressive, subacute course within 3 months. A high titer of anti-GQ1b antibodies was detected. As a result of plasmapheresis, complete recovery was achieved.

Conclusions

The presented case was atypical in its clinical course and treatment. It could support the theory of the continuity between MFS, Bickerstaff brainstem encephalitis (BBE), and Guillain–Barré syndrome (GBS).

Abstract

Background

Miller-Fisher Syndrome (MFS) is a rare acute polyneuropathy composed of the clinical triad of ataxia, areflexia and ophthalmoplegia, with a monophasic, self-limited course and spontaneous improvement.

Case report

The authors present a 65-year-old man with Miller-Fisher syndrome consisting of bilateral ophthalmoplegia, trigeminal and facial nerve palsy, mild ataxia and peripheral neuropathy. The disease had a progressive, subacute course within 3 months. A high titer of anti-GQ1b antibodies was detected. As a result of plasmapheresis, complete recovery was achieved.

Conclusions

The presented case was atypical in its clinical course and treatment. It could support the theory of the continuity between MFS, Bickerstaff brainstem encephalitis (BBE), and Guillain–Barré syndrome (GBS).

Get Citation

Keywords

Anti-GQ1b antibody, Miller-Fisher syndrome, Plasmapheresis

About this article
Title

Progressive subacute Miller-Fisher syndrome successfully treated with plasmapheresis

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 49, No 2 (2015)

Pages

137-138

DOI

10.1016/j.pjnns.2015.03.002

Bibliographic record

Neurol Neurochir Pol 2015;49(2):137-138.

Keywords

Anti-GQ1b antibody
Miller-Fisher syndrome
Plasmapheresis

Authors

Maria Ejma
Marta Waliszewska-Prosół
Anna Hofman
Sławomir Budrewicz
Ryszard Podemski
Małgorzata Bilińska
Magdalena Koszewicz

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