Vol 48, No 6 (2014)
Review Article

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Diagnosis and management of neuropathic pain: Review of literature and recommendations of the Polish Association for the Study of Pain and the Polish Neurological Society – Part Two

Andrzej Szczudlik1, Jan Dobrogowski2, Jerzy Wordliczek3, Adam Stępień4, Małgorzata Krajnik5, Wojciech Leppert6, Jarosław Woroń37, Anna Przeklasa-Muszyńska2, Magdalena Kocot-Kępska2, Renata Zajączkowska2, Marcin Janecki8, Anna Adamczyk5, Małgorzata Malec-Milewska9
DOI: 10.1016/j.pjnns.2014.11.002
Neurol Neurochir Pol 2014;48(6):423-435.


Neuropathic pain may be caused by a variety of lesions or diseases of both the peripheral and central nervous system. The most common and best known syndromes of peripheral neuropathic pain are painful diabetic neuropathy, trigeminal and post-herpetic neuralgia, persistent post-operative and post-traumatic pain, complex regional pain syndrome, cancer-related neuropathic pain, HIV-related neuropathic pain and pain after amputation. The less common central pain comprises primarily central post-stroke pain, pain after spinal cord injury, central pain in Parkinson disease or in other neurodegenerative diseases, pain in syringomyelia and in multiple sclerosis.

A multidisciplinary team of Polish experts, commissioned by the Polish Association for the Study of Pain and the Polish Neurological Society, has reviewed the literature on various types of neuropathic pain, with special focus on the available international guidelines, and has formulated recommendations on their diagnosis and treatment, in accordance with the principles of evidence-based medicine (EBM). High quality studies on the efficacy of various medicines and medical procedures in many neuropathic pain syndromes are scarce, which makes the recommendations less robust.

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Neurologia i Neurochirurgia Polska