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Small volume of the posterior cranial fossa and arterial hypertension are risk factors of hemifacial spasm
Affiliations- Department of Neurology, Medical University of Silesia, Katowice, Poland
- Department of Neurology, Jagiellonian University Medical College, Krakow, Poland
- Department of Neurology with Unit of Stroke and Unit of Neurological Rehabilitation, Hospital John Paul II, Kraków, Poland
- Medical Diagnostic Centres Voxel, Zabrze, Poland
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Abstract
So far, there are only two studies evaluating the relation between the small volume of the posterior cranial fossa (VPCF) and the occurrence of HFS, both on Asian population. The aim of the study was to determine small VPCF and arterial hypertension (AH), as risk factors for hemifacial spasm (HFS) and their relation to neurovascular conflict (NVC) in Polish Caucasian-origin patients.
Materials and methodsThe study included 60 patients with idiopathic HFS and 60 healthy volunteers matched by sex and age. AH was defined according to WHO. The VPCF measured the volume of the prepontine, prespinal and both cerebellopontine angle cisterns in MRI scans.
ResultsThere were no significant differences between occurrence of AH and the VPCF of patients and controls but the mean VPCF in women was significantly smaller than in men, In the multivariate regression analysis model only NVC was the statistically significant. In the subgroup of >50-year-old patients the most dominant risk factor was NVC (OR 71.09; 95% CI 21.08–239.77; p=0.0000), followed by the AH duration (OR 1.07; 95% CI 1.00–1.16; p=0.047). In the subgroup of <50 years, NVC was also the dominant risk factor, followed by the lower VPCF (Walad test: OR 0.4; 95% CI 0.16–1.04; p=0.045).
ConclusionThere was no significant difference in VPCF and in frequency of AH diagnosis in HFS patients and age- and sex-related controls, but the logistic regression analysis showed that small VPCF and AH duration are risk factors of HFS in younger and older patients respectively.
Abstract
So far, there are only two studies evaluating the relation between the small volume of the posterior cranial fossa (VPCF) and the occurrence of HFS, both on Asian population. The aim of the study was to determine small VPCF and arterial hypertension (AH), as risk factors for hemifacial spasm (HFS) and their relation to neurovascular conflict (NVC) in Polish Caucasian-origin patients.
Materials and methodsThe study included 60 patients with idiopathic HFS and 60 healthy volunteers matched by sex and age. AH was defined according to WHO. The VPCF measured the volume of the prepontine, prespinal and both cerebellopontine angle cisterns in MRI scans.
ResultsThere were no significant differences between occurrence of AH and the VPCF of patients and controls but the mean VPCF in women was significantly smaller than in men, In the multivariate regression analysis model only NVC was the statistically significant. In the subgroup of >50-year-old patients the most dominant risk factor was NVC (OR 71.09; 95% CI 21.08–239.77; p=0.0000), followed by the AH duration (OR 1.07; 95% CI 1.00–1.16; p=0.047). In the subgroup of <50 years, NVC was also the dominant risk factor, followed by the lower VPCF (Walad test: OR 0.4; 95% CI 0.16–1.04; p=0.045).
ConclusionThere was no significant difference in VPCF and in frequency of AH diagnosis in HFS patients and age- and sex-related controls, but the logistic regression analysis showed that small VPCF and AH duration are risk factors of HFS in younger and older patients respectively.
Keywords
Hemifacial spasm, Risk factors, Posterior cranial fossa
About this articleTitle
Small volume of the posterior cranial fossa and arterial hypertension are risk factors of hemifacial spasm
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
383-386
Page views
322
Article views/downloads
360
DOI
10.1016/j.pjnns.2014.09.006
Bibliographic record
Neurol Neurochir Pol 2014;48(6):383-386.
Keywords
Hemifacial spasm
Risk factors
Posterior cranial fossa
Authors
Monika Rudzińska
Magdalena Wójcik-Pędziwiatr
Michalina Malec
Natalia Grabska
Marcin Hartel
Andrzej Szczudlik
