open access

Vol 48, No 6 (2014)
Original research articles
Submitted: 2014-06-09
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Small volume of the posterior cranial fossa and arterial hypertension are risk factors of hemifacial spasm

Monika Rudzińska, Magdalena Wójcik-Pędziwiatr, Michalina Malec, Natalia Grabska, Marcin Hartel, Andrzej Szczudlik
DOI: 10.1016/j.pjnns.2014.09.006
·
Neurol Neurochir Pol 2014;48(6):383-386.

open access

Vol 48, No 6 (2014)
Original research articles
Submitted: 2014-06-09

Abstract

Objectives

So far, there are only two studies evaluating the relation between the small volume of the posterior cranial fossa (VPCF) and the occurrence of HFS, both on Asian population. The aim of the study was to determine small VPCF and arterial hypertension (AH), as risk factors for hemifacial spasm (HFS) and their relation to neurovascular conflict (NVC) in Polish Caucasian-origin patients.

Materials and methods

The study included 60 patients with idiopathic HFS and 60 healthy volunteers matched by sex and age. AH was defined according to WHO. The VPCF measured the volume of the prepontine, prespinal and both cerebellopontine angle cisterns in MRI scans.

Results

There were no significant differences between occurrence of AH and the VPCF of patients and controls but the mean VPCF in women was significantly smaller than in men, In the multivariate regression analysis model only NVC was the statistically significant. In the subgroup of >50-year-old patients the most dominant risk factor was NVC (OR 71.09; 95% CI 21.08–239.77; p=0.0000), followed by the AH duration (OR 1.07; 95% CI 1.00–1.16; p=0.047). In the subgroup of <50 years, NVC was also the dominant risk factor, followed by the lower VPCF (Walad test: OR 0.4; 95% CI 0.16–1.04; p=0.045).

Conclusion

There was no significant difference in VPCF and in frequency of AH diagnosis in HFS patients and age- and sex-related controls, but the logistic regression analysis showed that small VPCF and AH duration are risk factors of HFS in younger and older patients respectively.

Abstract

Objectives

So far, there are only two studies evaluating the relation between the small volume of the posterior cranial fossa (VPCF) and the occurrence of HFS, both on Asian population. The aim of the study was to determine small VPCF and arterial hypertension (AH), as risk factors for hemifacial spasm (HFS) and their relation to neurovascular conflict (NVC) in Polish Caucasian-origin patients.

Materials and methods

The study included 60 patients with idiopathic HFS and 60 healthy volunteers matched by sex and age. AH was defined according to WHO. The VPCF measured the volume of the prepontine, prespinal and both cerebellopontine angle cisterns in MRI scans.

Results

There were no significant differences between occurrence of AH and the VPCF of patients and controls but the mean VPCF in women was significantly smaller than in men, In the multivariate regression analysis model only NVC was the statistically significant. In the subgroup of >50-year-old patients the most dominant risk factor was NVC (OR 71.09; 95% CI 21.08–239.77; p=0.0000), followed by the AH duration (OR 1.07; 95% CI 1.00–1.16; p=0.047). In the subgroup of <50 years, NVC was also the dominant risk factor, followed by the lower VPCF (Walad test: OR 0.4; 95% CI 0.16–1.04; p=0.045).

Conclusion

There was no significant difference in VPCF and in frequency of AH diagnosis in HFS patients and age- and sex-related controls, but the logistic regression analysis showed that small VPCF and AH duration are risk factors of HFS in younger and older patients respectively.

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Keywords

Hemifacial spasm, Risk factors, Posterior cranial fossa

About this article
Title

Small volume of the posterior cranial fossa and arterial hypertension are risk factors of hemifacial spasm

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 48, No 6 (2014)

Pages

383-386

DOI

10.1016/j.pjnns.2014.09.006

Bibliographic record

Neurol Neurochir Pol 2014;48(6):383-386.

Keywords

Hemifacial spasm
Risk factors
Posterior cranial fossa

Authors

Monika Rudzińska
Magdalena Wójcik-Pędziwiatr
Michalina Malec
Natalia Grabska
Marcin Hartel
Andrzej Szczudlik

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