open access

Vol 48, No 4 (2014)
Review article
Submitted: 2014-07-04
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Diagnosis and management of neuropathic pain: Review of literature and recommendations of the Polish Association for the Study of Pain and the Polish Neurological Society – Part one

Andrzej Szczudlik, Jan Dobrogowski, Jerzy Wordliczek, Adam Stępień, Małgorzata Krajnik, Wojciech Leppert, Jarosław Woroń, Anna Przeklasa-Muszyńska, Magdalena Kocot-Kępska, Renata Zajączkowska, Marcin Janecki, Anna Adamczyk, Małgorzata Malec-Milewska
DOI: 10.1016/j.pjnns.2014.07.011
·
Neurol Neurochir Pol 2014;48(4):262-271.

open access

Vol 48, No 4 (2014)
Review article
Submitted: 2014-07-04

Abstract

Neuropathic pain still present a major diagnostic and therapeutic challenge despite considerable progress in understanding of its mechanisms and publication of number of studies which assessed the efficacy and safety of drugs used in the symptomatic treatment. In practice, it is diagnosed less frequently than recognised in the epidemiological studies, and many patients do not achieve satisfactory outcomes of treatment. A multidisciplinary team of Polish experts, commissioned by the Polish Association for the Study of Pain and the Polish Neurological Society, has reviewed the literature on neuropathic pain, with special focus on the published international recommendations, and formulated recommendations on neuropathic pain diagnosis and treatment, in accordance with the principles of evidence-based medicine. The paper presents also background information on the neuropathic pain definition, epidemiology, pathomechanism and method of assessment. The diagnosis of neuropathic pain may be established based on medical history and physical examination including special assessment of the somatosensory system. First-line drugs used in pharmacological management of neuropathic pain are: tricyclic antidepressants, serotonin and norepinephrine reuptake inhibitors, gabapentin, pregabalin, opioids and lidocaine patches.

Abstract

Neuropathic pain still present a major diagnostic and therapeutic challenge despite considerable progress in understanding of its mechanisms and publication of number of studies which assessed the efficacy and safety of drugs used in the symptomatic treatment. In practice, it is diagnosed less frequently than recognised in the epidemiological studies, and many patients do not achieve satisfactory outcomes of treatment. A multidisciplinary team of Polish experts, commissioned by the Polish Association for the Study of Pain and the Polish Neurological Society, has reviewed the literature on neuropathic pain, with special focus on the published international recommendations, and formulated recommendations on neuropathic pain diagnosis and treatment, in accordance with the principles of evidence-based medicine. The paper presents also background information on the neuropathic pain definition, epidemiology, pathomechanism and method of assessment. The diagnosis of neuropathic pain may be established based on medical history and physical examination including special assessment of the somatosensory system. First-line drugs used in pharmacological management of neuropathic pain are: tricyclic antidepressants, serotonin and norepinephrine reuptake inhibitors, gabapentin, pregabalin, opioids and lidocaine patches.

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Keywords

Neuropathic pain, Diagnosis of neuropathic pain, Assessment of neuropathic pain, Pharmacological treatment of neuropathic pain, Evidence-based recommendations

About this article
Title

Diagnosis and management of neuropathic pain: Review of literature and recommendations of the Polish Association for the Study of Pain and the Polish Neurological Society – Part one

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 48, No 4 (2014)

Pages

262-271

DOI

10.1016/j.pjnns.2014.07.011

Bibliographic record

Neurol Neurochir Pol 2014;48(4):262-271.

Keywords

Neuropathic pain
Diagnosis of neuropathic pain
Assessment of neuropathic pain
Pharmacological treatment of neuropathic pain
Evidence-based recommendations

Authors

Andrzej Szczudlik
Jan Dobrogowski
Jerzy Wordliczek
Adam Stępień
Małgorzata Krajnik
Wojciech Leppert
Jarosław Woroń
Anna Przeklasa-Muszyńska
Magdalena Kocot-Kępska
Renata Zajączkowska
Marcin Janecki
Anna Adamczyk
Małgorzata Malec-Milewska

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