Vol 48, No 2 (2014)
Review Article

open access

Page views 556
Article views/downloads 653
Get Citation

Connect on Social Media

Connect on Social Media

Alternating hemiplegia of childhood: New diagnostic options

Aleksandra Gergont1, Marek Kaciński1
DOI: 10.1016/j.pjnns.2013.05.003
Neurol Neurochir Pol 2014;48(2):130-135.


A syndrome of alternating hemiplegia of childhood (AHC) is a rare disorder first presented in 1971. AHC is characterized by transient episodes of hemiplegia affecting either one or both sides of the body. Age of onset is before 18 months and the common earliest manifestations are dystonic or tonic attacks and nystagmus. Hemiplegic episodes last minutes to days and the frequency and duration tend to decrease with time. Motor and intellectual development is affected, deficits may also develop later. Epileptic seizures occur in some patients. Neuroimaging of the brain usually reveals no abnormalities. The variability of individual clinical presentations and evolution of symptoms have made diagnosis difficult. Therefore the problems of misdiagnosis could account for the low prevalence of this syndrome. This paper hopes to present actual data on AHC, especially of the results of genetic research and new diagnostic tools.

Article available in PDF format

View PDF Download PDF file

Neurologia i Neurochirurgia Polska