open access

Vol 47, No 4 (2013)
OPIS PRZYPADKU
Submitted: 2012-07-06
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Effect of liver transplantation on brain magnetic resonance imaging pathology in Wilson disease: a case report

Tomasz Litwin, Karolina Dzieżyc, Renata Poniatowska, Anna Członkowska
DOI: 10.5114/ninp.2013.36763
·
Neurol Neurochir Pol 2013;47(4):393-397.

open access

Vol 47, No 4 (2013)
OPIS PRZYPADKU
Submitted: 2012-07-06

Abstract

The authors present a case report of a 28-year-old patient with hepatic, but no neurological, signs of Wilson disease, with pathological changes in both the globi pallidi and caudate found with routine brain magnetic resonance imaging (MRI). The patient was recommended for liver transplantation by hepatologists, and during the two years of observation after liver transplantation, MRI brain abnormalities due to Wilson disease completely regressed. On the basis of this case, the authors present an argument for the prognostic significance of brain MRI in Wilson disease as well as current recommendations concerning liver transplantation in Wilson disease.

Abstract

The authors present a case report of a 28-year-old patient with hepatic, but no neurological, signs of Wilson disease, with pathological changes in both the globi pallidi and caudate found with routine brain magnetic resonance imaging (MRI). The patient was recommended for liver transplantation by hepatologists, and during the two years of observation after liver transplantation, MRI brain abnormalities due to Wilson disease completely regressed. On the basis of this case, the authors present an argument for the prognostic significance of brain MRI in Wilson disease as well as current recommendations concerning liver transplantation in Wilson disease.

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Keywords

Wilson disease, liver transplantation, copper metabolism

About this article
Title

Effect of liver transplantation on brain magnetic resonance imaging pathology in Wilson disease: a case report

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 47, No 4 (2013)

Pages

393-397

DOI

10.5114/ninp.2013.36763

Bibliographic record

Neurol Neurochir Pol 2013;47(4):393-397.

Keywords

Wilson disease
liver transplantation
copper metabolism

Authors

Tomasz Litwin
Karolina Dzieżyc
Renata Poniatowska
Anna Członkowska

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