Vol 47, No 4 (2013)

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Effect of liver transplantation on brain magnetic resonance imaging pathology in Wilson disease: a case report

Tomasz Litwin1, Karolina Dzieżyc1, Renata Poniatowska2, Anna Członkowska13
DOI: 10.5114/ninp.2013.36763
Neurol Neurochir Pol 2013;47(4):393-397.


The authors present a case report of a 28-year-old patient with hepatic, but no neurological, signs of Wilson disease, with pathological changes in both the globi pallidi and caudate found with routine brain magnetic resonance imaging (MRI). The patient was recommended for liver transplantation by hepatologists, and during the two years of observation after liver transplantation, MRI brain abnormalities due to Wilson disease completely regressed. On the basis of this case, the authors present an argument for the prognostic significance of brain MRI in Wilson disease as well as current recommendations concerning liver transplantation in Wilson disease.

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Neurologia i Neurochirurgia Polska