The age of the patient at the onset of the disease may influence its course and outcome of the treatment. The objective of this study was to compare outcomes of carpal tunnel release in patients in different age ranges.

The records from the register of patients with carpal tunnel syndrome who were operated on in the authors’ department over a period of two years (between 2009 and 2011) were analyzed. A total of 386 patients with carpal tunnel syndrome, 322 female (83%) and 64 male (17%) with a mean age of 57 (range: 30–81) years were divided into three sub-groups according to their age: 40 years or less (n = = 28), 41–65 years (n = 248) and over 65 years (n = 73). All patients received mini-open carpal tunnel release. The results were assessed at 6 months after the operation by the Levine questionnaire and measurements of grip and pinch strengths as well as sensation of a light touch by the filament test.

At the six-month follow-up, all patients showed significant resolution of symptoms as assessed by the Levine symptom score (from 3.3 to 1.4) and significant improvement of the dexterity of the hand, as assessed by the Levine function score (from 3.0–3.2 to 1.6–1.8). All patients showed significant improvement of sensation of a light touch and increase of grip and pinch strengths. However, patients older than 60 years showed less improvement of the total grip strength of the hand.

Patients with carpal tunnel syndrome at any age may expect a similar benefit from surgery.