open access

Vol 47, No 2 (2013)
OPIS PRZYPADKU
Submitted: 2012-02-02
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A case of a solitary form of Castleman disease: ten-year follow-up

Grzegorz Turek, Joanna Reszeć, Jan Kochanowicz, Adam Hermanowicz, Zenon Mariak
DOI: 10.5114/ninp.2013.34636
·
Neurol Neurochir Pol 2013;47(2):179-183.

open access

Vol 47, No 2 (2013)
OPIS PRZYPADKU
Submitted: 2012-02-02

Abstract

Castleman disease (CD) is a rare atypical lymphoproliferative process of obscure pathogenesis. An intracranial localization of the condition is extremely rare. We present a case of a 29-year-old man, who harbored an intracranial plasma cell variant of CD in the form of a tumor mimicking meningioma and was followed up to 10 years after surgical excision of the lesion. The histopathological examination showed massive infiltration of mononuclear cells, composed mainly of lymphocytes and matured plasmocytes, as well as many small thin-walled vessels surrounded with plasma cells and lymphocytes. This picture was consistent with a plasma cell type of CD. Ten-year follow-up supports a notion that total surgical excision of the solitary intracranial infiltration is curative in plasma cell type of CD.

Abstract

Castleman disease (CD) is a rare atypical lymphoproliferative process of obscure pathogenesis. An intracranial localization of the condition is extremely rare. We present a case of a 29-year-old man, who harbored an intracranial plasma cell variant of CD in the form of a tumor mimicking meningioma and was followed up to 10 years after surgical excision of the lesion. The histopathological examination showed massive infiltration of mononuclear cells, composed mainly of lymphocytes and matured plasmocytes, as well as many small thin-walled vessels surrounded with plasma cells and lymphocytes. This picture was consistent with a plasma cell type of CD. Ten-year follow-up supports a notion that total surgical excision of the solitary intracranial infiltration is curative in plasma cell type of CD.

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Keywords

Castleman disease, meningioma-like lesion, surgical treatment

About this article
Title

A case of a solitary form of Castleman disease: ten-year follow-up

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 47, No 2 (2013)

Pages

179-183

DOI

10.5114/ninp.2013.34636

Bibliographic record

Neurol Neurochir Pol 2013;47(2):179-183.

Keywords

Castleman disease
meningioma-like lesion
surgical treatment

Authors

Grzegorz Turek
Joanna Reszeć
Jan Kochanowicz
Adam Hermanowicz
Zenon Mariak

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