open access
Primary intracranial basaloid squamous cell carcinoma: an enigma
Affiliations- Department of Radiotherapy & Oncology, All India Institute of Medical Sciences, New Delhi, India
- Acibadem Hospital, Department of Pathology, Istanbul/TURKEY, 34718 Istanbul, Türkiye
- Ankara University Faculty of Medicine, Department of Nuclear Medicine, İbni Sina Hospital, 06410 Ankara, Türkiye
open access
Abstract
Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from malignant transformation of dysembryogenetic lesions such as epidermoid and dermoid cysts. Intracranial squamous cell neoplasm arising de novo is even rarer and has been reported in only four patients to date. We herein describe a case of primary intracranial squamous cell carcinoma arising de novo in the right frontal lobe in a 35-year-old woman treated with a combination of surgery and postoperative conformal radiation. We have also shed light on the biology and the therapeutic options of this enigmatic tumour.
Abstract
Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from malignant transformation of dysembryogenetic lesions such as epidermoid and dermoid cysts. Intracranial squamous cell neoplasm arising de novo is even rarer and has been reported in only four patients to date. We herein describe a case of primary intracranial squamous cell carcinoma arising de novo in the right frontal lobe in a 35-year-old woman treated with a combination of surgery and postoperative conformal radiation. We have also shed light on the biology and the therapeutic options of this enigmatic tumour.
Keywords
squamous cell carcinoma, intracranial, basaloid
About this articleTitle
Primary intracranial basaloid squamous cell carcinoma: an enigma
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
489-495
Page views
341
Article views/downloads
542
DOI
10.5114/ninp.2012.31361
Bibliographic record
Neurol Neurochir Pol 2012;46(5):489-495.
Keywords
squamous cell carcinoma
intracranial
basaloid
Authors
Supriya Mallick
Ahitagni Biswas
Narender Kumar
Mehar Chand Sharma
Rakesh Kumar
Rama Mohan Reddy
Pramod Kumar Julka
Goura Kishore Rath
