Vol 46, No 5 (2012)

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Primary intracranial basaloid squamous cell carcinoma: an enigma

Supriya Mallick1, Ahitagni Biswas1, Narender Kumar2, Mehar Chand Sharma2, Rakesh Kumar3, Rama Mohan Reddy3, Pramod Kumar Julka1, Goura Kishore Rath1
DOI: 10.5114/ninp.2012.31361
Neurol Neurochir Pol 2012;46(5):489-495.

Abstract

Primary intracranial squamous cell carcinoma is extremely rare, with most cases arising from malignant transformation of dysembryogenetic lesions such as epidermoid and dermoid cysts. Intracranial squamous cell neoplasm arising de novo is even rarer and has been reported in only four patients to date. We herein describe a case of primary intracranial squamous cell carcinoma arising de novo in the right frontal lobe in a 35-year-old woman treated with a combination of surgery and postoperative conformal radiation. We have also shed light on the biology and the therapeutic options of this enigmatic tumour.

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Neurologia i Neurochirurgia Polska