open access

Vol 46, No 4 (2012)
ARTYKUŁ ORYGINALNY
Submitted: 2011-12-26
Get Citation

Poor insight into memory impairment in patients with Huntington disease

Emilia J. Sitek, Witold Sołtan, Piotr Robowski, Michał Schinwelski, Dariusz Wieczorek, Jarosław Sławek
DOI: 10.5114/ninp.2012.30262
·
Neurol Neurochir Pol 2012;46(4):318-325.

open access

Vol 46, No 4 (2012)
ARTYKUŁ ORYGINALNY
Submitted: 2011-12-26

Abstract

Background and purpose

Patients suffering from Huntington disease (HD) have been shown to present with poor self-awareness of a variety of symptoms. The study aimed to assess the self-awareness of memory impairment in HD in comparison to advanced Parkinson disease (PD), mild PD and cervical dystonia.

Material and methods

Self-awareness was tested in 23 patients with HD by comparing patient and caregiver ratings in reference to clinical control groups (25 patients with advanced PD, 21 with mild PD and 20 with cervical dystonia). Self-awareness was tested using the Self Rating Scale of Memory Functions, which was administered to both the patients and the caregivers. Neuropsychological assessment addressed general cognitive status (Mini-Mental State Examination), verbal learning (Auditory Verbal Learning Test, 15-word list) and mood (Montgomery-Asberg Depression Rating Scale).

Results

Patients with HD significantly underestimated their memory dysfunction. Underestimation of memory deficit correlated with disease duration and disease severity in HD.

Conclusions

Huntington disease patients underestimate memory dysfunction. These results add to the previous reports on poor insight in HD in other domains and suggest that anosognosia in HD, albeit usually rather mild, may be a generalized phenomenon.

Abstract

Background and purpose

Patients suffering from Huntington disease (HD) have been shown to present with poor self-awareness of a variety of symptoms. The study aimed to assess the self-awareness of memory impairment in HD in comparison to advanced Parkinson disease (PD), mild PD and cervical dystonia.

Material and methods

Self-awareness was tested in 23 patients with HD by comparing patient and caregiver ratings in reference to clinical control groups (25 patients with advanced PD, 21 with mild PD and 20 with cervical dystonia). Self-awareness was tested using the Self Rating Scale of Memory Functions, which was administered to both the patients and the caregivers. Neuropsychological assessment addressed general cognitive status (Mini-Mental State Examination), verbal learning (Auditory Verbal Learning Test, 15-word list) and mood (Montgomery-Asberg Depression Rating Scale).

Results

Patients with HD significantly underestimated their memory dysfunction. Underestimation of memory deficit correlated with disease duration and disease severity in HD.

Conclusions

Huntington disease patients underestimate memory dysfunction. These results add to the previous reports on poor insight in HD in other domains and suggest that anosognosia in HD, albeit usually rather mild, may be a generalized phenomenon.

Get Citation

Keywords

Huntington disease, verbal learning, awareness

About this article
Title

Poor insight into memory impairment in patients with Huntington disease

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 46, No 4 (2012)

Pages

318-325

DOI

10.5114/ninp.2012.30262

Bibliographic record

Neurol Neurochir Pol 2012;46(4):318-325.

Keywords

Huntington disease
verbal learning
awareness

Authors

Emilia J. Sitek
Witold Sołtan
Piotr Robowski
Michał Schinwelski
Dariusz Wieczorek
Jarosław Sławek

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: viamedica@viamedica.pl