Vol 46, No 3 (2012)

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Guillain-Barré syndrome as the first manifestation of POEMS syndrome

Monika Sójka1, Agata Gajos12, Justyna Pigońska12, Marek Bogucki1, Krzysztof Tyfa3, Andrzej Bogucki12
DOI: 10.5114/ninp.2012.29136
Neurol Neurochir Pol 2012;46(3):284-287.


POEMS syndrome is a rare multisystem disorder, characterized by the presence of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes. The variety of clinical pictures and asynchronous manifestation of dominant features make diagnosis difficult. We report a case of a 42-year-old man with polyneuropathy who was initially negative for monoclonal protein and so Guillain-Barré syndrome was diagnosed. Other signs and symptoms, including monoclonal gammopathy, developed later in the course of the disease and finally POEMS syndrome was diagnosed.

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Neurologia i Neurochirurgia Polska