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Guillain-Barré syndrome as the first manifestation of POEMS syndrome
Affiliations- Kliniczny Oddział Neurologii z Pododdziałem Chorób Układu Pozapiramidowego, III Szpital Miejski im. dr. Karola Jonschera w Lodzi
- Klinika Chorób Pozapiramidowych, Uniwersytet Medyczny w Łodzi
- Katedra i Zakład Radiologii i Radiodiagnostyki Lekarskiej, Samodzielny Publiczny Szpital Kliniczny nr 1 w Zabrzu, Śląski Uniwersytet Medyczny
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Abstract
POEMS syndrome is a rare multisystem disorder, characterized by the presence of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes. The variety of clinical pictures and asynchronous manifestation of dominant features make diagnosis difficult. We report a case of a 42-year-old man with polyneuropathy who was initially negative for monoclonal protein and so Guillain-Barré syndrome was diagnosed. Other signs and symptoms, including monoclonal gammopathy, developed later in the course of the disease and finally POEMS syndrome was diagnosed.
Abstract
POEMS syndrome is a rare multisystem disorder, characterized by the presence of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes. The variety of clinical pictures and asynchronous manifestation of dominant features make diagnosis difficult. We report a case of a 42-year-old man with polyneuropathy who was initially negative for monoclonal protein and so Guillain-Barré syndrome was diagnosed. Other signs and symptoms, including monoclonal gammopathy, developed later in the course of the disease and finally POEMS syndrome was diagnosed.
Keywords
POEMS syndrome, polyneuropathy, monoclonal protein
About this articleTitle
Guillain-Barré syndrome as the first manifestation of POEMS syndrome
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
284-287
Page views
252
Article views/downloads
459
DOI
10.5114/ninp.2012.29136
Bibliographic record
Neurol Neurochir Pol 2012;46(3):284-287.
Keywords
POEMS syndrome
polyneuropathy
monoclonal protein
Authors
Monika Sójka
Agata Gajos
Justyna Pigońska
Marek Bogucki
Krzysztof Tyfa
Andrzej Bogucki
