open access

Vol 46, No 1 (2012)
OPIS PRZYPADKU
Submitted: 2011-02-02
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Primary intracranial extraskeletal myxoid chondrosarcoma

Renaud Dulou, Cyrus Chargari, Arnaud Dagain, Christophe Teriitehau, Olivier Goasguen, Olivier Jeanjean, Lionel Védrine
DOI: 10.5114/ninp.2012.27176
·
Neurol Neurochir Pol 2012;46(1):76-81.

open access

Vol 46, No 1 (2012)
OPIS PRZYPADKU
Submitted: 2011-02-02

Abstract

Extraskeletal myxoid chondrosarcomas (EMC) are extremely rare and are usually located in the deep soft tissues of the lower extremities. Less than 10 cases of intracranial EMC have been reported in the literature, making their management and early diagnosis difficult. We present a new case of intracranial EMC occurring in a 70-year-old woman presenting with a right frontal mass initially assumed to be a brain metastasis from breast adenocarcinoma. The optimal management of these tumours is also discussed. Analysis from the literature suggests that complete resection should be recommended, whenever feasible. Although the high risk for relapse after surgery encourages postoperative treatments, relative resistance to both radiotherapy and chemotherapy characterizes EMC. Future perspectives might include multimodal treatments with highly conformal radiotherapy modalities for dose escalation strategies or use of new molecules. Knowledge of these unusual malignant tumours will be the first step for improving patients’ outcome.

Abstract

Extraskeletal myxoid chondrosarcomas (EMC) are extremely rare and are usually located in the deep soft tissues of the lower extremities. Less than 10 cases of intracranial EMC have been reported in the literature, making their management and early diagnosis difficult. We present a new case of intracranial EMC occurring in a 70-year-old woman presenting with a right frontal mass initially assumed to be a brain metastasis from breast adenocarcinoma. The optimal management of these tumours is also discussed. Analysis from the literature suggests that complete resection should be recommended, whenever feasible. Although the high risk for relapse after surgery encourages postoperative treatments, relative resistance to both radiotherapy and chemotherapy characterizes EMC. Future perspectives might include multimodal treatments with highly conformal radiotherapy modalities for dose escalation strategies or use of new molecules. Knowledge of these unusual malignant tumours will be the first step for improving patients’ outcome.

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Keywords

intracranial tumour, extraskeletal myxoid chondrosarcoma, brain neoplasm

About this article
Title

Primary intracranial extraskeletal myxoid chondrosarcoma

Journal

Neurologia i Neurochirurgia Polska

Issue

Vol 46, No 1 (2012)

Pages

76-81

DOI

10.5114/ninp.2012.27176

Bibliographic record

Neurol Neurochir Pol 2012;46(1):76-81.

Keywords

intracranial tumour
extraskeletal myxoid chondrosarcoma
brain neoplasm

Authors

Renaud Dulou
Cyrus Chargari
Arnaud Dagain
Christophe Teriitehau
Olivier Goasguen
Olivier Jeanjean
Lionel Védrine

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