Vol 45, No 1 (2011)

open access

Page views 526
Article views/downloads 656
Get Citation

Connect on Social Media

Connect on Social Media

Subthalamic deep brain stimulation for the treatment of Parkinson disease

Tomasz Mandat12, Tomasz Tykocki2, Henryk Koziara12, Dariusz Koziorowski3, Bogdan Brodacki3, Rafał Rola45, Wiesław Bonicki12, Pawel Nauman12
DOI: 10.1016/S0028-3843(14)60057-8
Neurol Neurochir Pol 2011;45(1):32-36.


Background and purpose

The role of subthalamic nucleus deep brain stimulation (STN DBS) in the treatment of Parkinson disease (PD) is well established. The authors present a group of patients diagnosed with PD who were treated with STN DBS.

Material and methods

Between 2008 and 2009, 32 female and 34 male patients with PD were treated with STN DBS. Mean age at implantation was 57 ± 12 years. PD lasted from 6 to 21 years (mean 10 years). Patients were qualified for the surgery according to the CAPSIT-PD criteria. The STN was identified with direct and indirect methods. Macrostimulation and microrecording for STN identification were used in all cases. A unilateral STN DBS system was implanted in two cases and bilateral implantation was performed among rest of the group. Outcome was assessed six months after implantation.


The mean reduction of UPDRS III score among 51 patients who underwent follow-up was 45% (5-89%). Reduction of levodopa consumption varied from 15 to 100%. Infection forced the authors to remove the DBS system in one case four months after implantation. Skin erosion above the internal pulse generator was noted in four cases.


Cardinal symptoms of Parkinson's disease can be safely and effectively treated with STN DBS in selected group of patients.

Article available in PDF format

View PDF Download PDF file

Neurologia i Neurochirurgia Polska