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Cerebral metastasis of a primary heart sarcoma
Affiliations- department of neurosurgery
- Institute of Pathology, Friedrich-Alexander-University of Erlangen-Nuremberg
- SKP Services, Dresden, Germany
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Abstract
Primary cardiac sarcomas are exceptionally rare tumours. A brain metastasis of a primary cardiac sarcoma has never been reported before. Although we know lots of primary malignomas spreading to the brain, we never observed cerebral metastases of an atrial spindle cell sarcoma. Cardiac sarcomas are more likely to haematogenously metastasize to the lung or the liver.
Here, we describe the case of a young man, who suffered from a cerebral metastasis of a spindle cell sarcoma in the left heart atrium nine years ago. Postoperative whole brain irradiation with 30 Gy was performed. Later on, the patient experienced a local recurrence within the left atrium accompanied by cardiac arrhythmia and mitral valve insufficiency. This case is the very first description of a true cerebral metastasis from a primary heart sarcoma. Therefore, clear treatment paradigms are not established. Further case illustrations and the publication of larger patient series are mandatory, whenever possible.
Abstract
Primary cardiac sarcomas are exceptionally rare tumours. A brain metastasis of a primary cardiac sarcoma has never been reported before. Although we know lots of primary malignomas spreading to the brain, we never observed cerebral metastases of an atrial spindle cell sarcoma. Cardiac sarcomas are more likely to haematogenously metastasize to the lung or the liver.
Here, we describe the case of a young man, who suffered from a cerebral metastasis of a spindle cell sarcoma in the left heart atrium nine years ago. Postoperative whole brain irradiation with 30 Gy was performed. Later on, the patient experienced a local recurrence within the left atrium accompanied by cardiac arrhythmia and mitral valve insufficiency. This case is the very first description of a true cerebral metastasis from a primary heart sarcoma. Therefore, clear treatment paradigms are not established. Further case illustrations and the publication of larger patient series are mandatory, whenever possible.
Keywords
primary cardiac sarcoma, brain metastasis, mitral valve insufficiency, neoadjuvant chemotherapy, adjuvant chemotherapy
About this articleTitle
Cerebral metastasis of a primary heart sarcoma
Journal
Neurologia i Neurochirurgia Polska
Issue
Pages
188-195
Page views
284
Article views/downloads
524
DOI
10.1016/S0028-3843(14)60010-4
Bibliographic record
Neurol Neurochir Pol 2010;44(2):188-195.
Keywords
primary cardiac sarcoma
brain metastasis
mitral valve insufficiency
neoadjuvant chemotherapy
adjuvant chemotherapy
Authors
Susanne A. Kuhn
Jan Walter
Iver Petersen
Ulrike Mueller
Rupert Reichart
Rolf Kalff
