Vol 5, No 2 (2020)
Case report
Published online: 2020-04-07

open access

Page views 503
Article views/downloads 839
Get Citation

Connect on Social Media

Connect on Social Media

Wound bed preparation for skin transplantation in chronic vein ulcers: A clinical case

Ingrida Ašakienė1, Greta Mickeviciute2, Rugilė Bražinskaitė2
Medical Research Journal 2020;5(2):116-119.


Introduction: Chronic vein ulcer treatment is a clinical challenge for vascular surgeons, which requires a complex approach.

Case presentation:
A 75-year-old male patient came to our out-patient clinic with a chronic trophic ulcer for five
years. The patient was previously unsuccessfully treated with zinc-gelatine impregnated bandages. Our treatment plan consisted of systemic antimicrobial therapy, which was prescribed by our clinical pharmacologist,
surgical debridement, phlebectomy, as well as split-thickness skin transplantation. The patient was released from the hospital after 14 days. No signs of infection were seen during the healing time.

A complex approach is recommended while treating chronic vein ulcers. Skin grafting reduces the duration and cost of the treatment.

Article available in PDF format

View PDF Download PDF file


  1. Attinger C, Wolcott R. Clinically Addressing Biofilm in Chronic Wounds. Adv Wound Care (New Rochelle). 2012; 1(3): 127–132.
  2. Margolis DJ, Berlin JA, Strom BL. Which venous leg ulcers will heal with limb compression bandages? Am J Med. 2000; 109(1): 15–19.
  3. Wax MK, Pittman AL, Ghanem TA. Split-thickness skin grafts: overview, graft selection, donor site selection, wound preparation, operative technique, graft survival, graft failure, biological skin substitutes. Medscape. 2019.
  4. Bobek K, Cajzl L, Cepelak V, et al. Étude de la fréquence des maladies phlébologiques et de l´influence de quelques facteurs étiologiques. Phlebologie. 1966; 19: 227–230.
  5. Widmer LK. Peripheral Venous Disorders. Basle Study III. Hans Huber, Bern 1978.
  6. Snyder RJ. Treatment of nonhealing ulcers with allografts. Clin Dermatol. 2005; 23(4): 388–395.
  7. Cronenwett JL, Johnston KW. (ed.). Rutherford‘s Vascular Surgery, 8th ed. Saunders Elsavier, Philadelphia 2014.
  8. Djalalov S, Sehatzadeh S, Keast DH, et al. Health Quality Ontario . Compression Stockings for the Prevention of Venous Leg Ulcer Recurrence: A Health Technology Assessment. Ont Health Technol Assess Ser. 2019; 19(2): 1–86.
  9. Bjarnsholt T, Eberlein T, Malone M, et al. et.al. Management of wound biofilm made easy. Wounds UK. 2017; 8(2): 1–6.
  10. Serra R, Rizzuto A, Rossi A, et al. Skin grafting for the treatment of chronic leg ulcers - a systematic review in evidence-based medicine. Int Wound J. 2017; 14(1): 149–157.