Online first
Images in medicine
Published online: 2024-08-08
Antiangiogenic effects in the modulation of inflammatory pathways. A comprehensive analysis of potential therapeutic substances.
DOI: 10.5603/mrj.101851
Abstract
Based on current knowledge antiangiogenic compounds are utilized in the treatment of inflammatory-depended diseases such as cancer. It has been shown that these compounds can simultaneously block several signaling pathways regulating angiogenesis. The visualization of fluorescently labeled F-actin and VE-cadherin was allowed to demonstrate that the reorganization of the cell cytoskeleton disrupts cellular processes and consequently inhibits angiogenesis.
Keywords: cell communicationinflammationantiangiogensis
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