Tom 10, Nr 1 (2017)
Artykuł przeglądowy
Opublikowany online: 2017-04-04
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Postępowanie z dziećmi chorymi na hemofilię powikłaną inhibitorem
Journal of Transfusion Medicine 2017;10(1):12-18.
Streszczenie
Wystąpienie inhibitora przeciwko preparatom koncentratów czynników krzepnięcia VIII lub
IX podawanym w trakcie leczenia chorych na hemofilię A lub B jest poważnym powikłaniem
choroby. Obecność inhibitora jest przyczyną braku skuteczności zastosowanego leczenia substytucyjnego,
dlatego w leczeniu hemofilii powikłanej inhibitorem hamowanie krwawień stanowi
cel doraźny, natomiast celem podstawowym jest trwała eliminacja inhibitora. W artykule
przedstawiono postępowanie w przypadku dzieci chorych na hemofilię powikłaną inhibitorem.
Słowa kluczowe: hemofiliainhibitorwywoływanie tolerancji immunologicznej (ITI)dzieci
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