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Tom 7, Nr 3 (2014)
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Opublikowany online: 2014-10-23

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Eksport do Mediów Społecznościowych

Eksport do Mediów Społecznościowych

Udział płytek krwi w procesach zapalnych

Krystyna Maślanka
Journal of Transfusion Medicine 2014;7(3):102-109.

Streszczenie

Płytki krwi są postrzegane przede wszystkim jako komórki biorące udział w procesach hemostazy naczyniowej i utrzymaniu integralności ściany naczyniowej. Nie do końca znana jest natomiast ich rola w procesach zapalnych, które powiązane są z aktywnością wrodzonego układu odporności immunologicznej. W pracy zostaną omówione między innymi wydzielane z ziarnistości płytek krwi związki (cytokiny/chemokiny), które przy współudziale komórek śródbłonka rekrutują leukocyty do miejsca zapalenia, receptory TLR (Toll-like receptors) płytek uczestniczące w rozpoznawaniu obcego patogenu oraz zostaną opisane mechanizmy prowadzące do udziału płytek krwi w procesach zapalnych. Niniejsza praca ma na celu uproszczone przedstawienie wpływu płytek krwi na funkcjonowanie skomplikowanego systemu wrodzonej odpowiedzi immunologicznej.

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Journal of Transfusion Medicine