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Vol 89, No 5 (2018)
Research paper
Published online: 2018-05-30
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Postnatal verification of prenatal diagnoses established on foetal magnetic resonance imaging

Agnieszka Duczkowska1, Anna Olwert2, Marek Duczkowski1, Monika Bekiesińska-Figatowska1
DOI: 10.5603/GP.a2018.0045
·
Pubmed: 30084478
·
Ginekol Pol 2018;89(5):262-270.
Affiliations
  1. Institute of Mother and Child, Kasprzaka 17A, 01-211 Warsaw, Poland
  2. Systems Research Institute, Polish Academy of Sciences, Newelska 6, 01-447 Warsaw, Poland

open access

Vol 89, No 5 (2018)
ORIGINAL PAPERS Obstetrics
Published online: 2018-05-30

Abstract

Objectives: The role of magnetic resonance imaging, similarly to ultrasound, in the evaluation of foetal anomalies is in­disputable. This gives rise to a question, whether prenatal diagnostics can replace postnatal one. To assess the diagnostic accuracy of foetal MRI in children with congenital anomalies by using postnatal MRI, X-ray/US and surgery (histopathol­ogy/autopsy) results as a reference standard.

Material and methods: 110 children were included in the analysis. All of them underwent foetal MRI, and the diagnoses were verified after birth. All the results were analysed both by: 1. evaluation of correctness of the prenatal diagnosis with the reference standard diagnosis of each patient, and 2. statistical evaluation of prenatal diagnosis using standard measures of binary diagnostic tests’ abilities.

Results: The accordance of prenatal and final diagnoses was 70%. Only 3.64% of patients were misdiagnosed. Most of the prenatal diagnoses that were incomplete (23.64%), concerned children who underwent surgery, and among them patients with abdominal cystic laesions of undetermined origin on foetal MRI constituted the majority. In 2.73% of cases prenatal diagnoses remained inconclusive.

Conclusions: High correlation of prenatal and postnatal tests’ results in the study material confirms the high value of foetal MRI in perinatal diagnostics. Comprehensive assessment of the foetus in prenatal MRI is very effective and facilitates impor­tant therapeutic decisions in the prenatal period (in utero treatment) and in perinatal care (application or withdrawal from the EXIT procedure, surgery or backtracking from neonatal resuscitation if it should bear the hallmarks of persistent therapy).

Abstract

Objectives: The role of magnetic resonance imaging, similarly to ultrasound, in the evaluation of foetal anomalies is in­disputable. This gives rise to a question, whether prenatal diagnostics can replace postnatal one. To assess the diagnostic accuracy of foetal MRI in children with congenital anomalies by using postnatal MRI, X-ray/US and surgery (histopathol­ogy/autopsy) results as a reference standard.

Material and methods: 110 children were included in the analysis. All of them underwent foetal MRI, and the diagnoses were verified after birth. All the results were analysed both by: 1. evaluation of correctness of the prenatal diagnosis with the reference standard diagnosis of each patient, and 2. statistical evaluation of prenatal diagnosis using standard measures of binary diagnostic tests’ abilities.

Results: The accordance of prenatal and final diagnoses was 70%. Only 3.64% of patients were misdiagnosed. Most of the prenatal diagnoses that were incomplete (23.64%), concerned children who underwent surgery, and among them patients with abdominal cystic laesions of undetermined origin on foetal MRI constituted the majority. In 2.73% of cases prenatal diagnoses remained inconclusive.

Conclusions: High correlation of prenatal and postnatal tests’ results in the study material confirms the high value of foetal MRI in perinatal diagnostics. Comprehensive assessment of the foetus in prenatal MRI is very effective and facilitates impor­tant therapeutic decisions in the prenatal period (in utero treatment) and in perinatal care (application or withdrawal from the EXIT procedure, surgery or backtracking from neonatal resuscitation if it should bear the hallmarks of persistent therapy).

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Keywords

foetal magnetic resonance imaging (MRI), congenital anomalies, prenatal diagnosis, postnatal diagnosis

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About this article
Title

Postnatal verification of prenatal diagnoses established on foetal magnetic resonance imaging

Journal

Ginekologia Polska

Issue

Vol 89, No 5 (2018)

Article type

Research paper

Pages

262-270

Published online

2018-05-30

Page views

1551

Article views/downloads

1157

DOI

10.5603/GP.a2018.0045

Pubmed

30084478

Bibliographic record

Ginekol Pol 2018;89(5):262-270.

Keywords

foetal magnetic resonance imaging (MRI)
congenital anomalies
prenatal diagnosis
postnatal diagnosis

Authors

Agnieszka Duczkowska
Anna Olwert
Marek Duczkowski
Monika Bekiesińska-Figatowska

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