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Vol 84, No 9 (2013)
ARTICLES
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Effects of the cigarette smoking on the newborn clinikal parametrs and the accumulation of cadmium and lead in the placenta of women from Upper Silesia

Katarzyna Suprewicz, Iwona Kozikowska, Magdalena Chrobaczyńska-Dyląg, Anna Gał, Anna Piekarz, Jerzy Sikora, Helena Sławska, Robert Stawarz
DOI: 10.17772/gp/1639
·
Ginekol Pol 2013;84(9).

open access

Vol 84, No 9 (2013)
ARTICLES

Abstract

Aim: The aim of the study was to determine the content of cadmium and lead in different parts of the placenta and fetal membranes of women who were exposed to cigarette smoke. The correlation between the two chemical elements and the impact of the Cd and Pb accumulation on newborn parameters were established. Materials and methods: The study material was collected immediately after delivery from 40 patients of the Department of Obstetrics and Gynecology, Katowice. The marginal and central parts of the placenta and fetal membranes (amnion) were taken. The women were divided into two groups: smokers and non-smokers. Metal concentration in placenta was determined by flame atomic absorption spectrometry (FAAS). Bioethical Commission approved of the study. Results: In both studied groups, smokers and non-smokers, the presence of cadmium and lead was detected. Smokers turned out to have accumulated more of the investigated heavy metals in the placenta and fetal membranes. In the analyzed groups of women of smokers and non-smokers, differences in the content of the studied metals were found, but they were not statistically significant. Differences in newborn parameters in the two groups of women occurred, but again they lacked statistical significance. The level of lead increases along with the increase in the amount of cadmium, which proves the existence of a statistically significant correlation between them (p = 0.000). Conclusions: The number of smoked cigarettes increases cadmium content in maternal placenta and fetal membranes. No significant differences in newborn parameters of either smoker or non-smokers were observed, which may indicate women’s adaptation to the environment containing cigarette smoke. The placenta and fetal membranes are biomarkers of the level of toxic exposure for the developing baby.

Abstract

Aim: The aim of the study was to determine the content of cadmium and lead in different parts of the placenta and fetal membranes of women who were exposed to cigarette smoke. The correlation between the two chemical elements and the impact of the Cd and Pb accumulation on newborn parameters were established. Materials and methods: The study material was collected immediately after delivery from 40 patients of the Department of Obstetrics and Gynecology, Katowice. The marginal and central parts of the placenta and fetal membranes (amnion) were taken. The women were divided into two groups: smokers and non-smokers. Metal concentration in placenta was determined by flame atomic absorption spectrometry (FAAS). Bioethical Commission approved of the study. Results: In both studied groups, smokers and non-smokers, the presence of cadmium and lead was detected. Smokers turned out to have accumulated more of the investigated heavy metals in the placenta and fetal membranes. In the analyzed groups of women of smokers and non-smokers, differences in the content of the studied metals were found, but they were not statistically significant. Differences in newborn parameters in the two groups of women occurred, but again they lacked statistical significance. The level of lead increases along with the increase in the amount of cadmium, which proves the existence of a statistically significant correlation between them (p = 0.000). Conclusions: The number of smoked cigarettes increases cadmium content in maternal placenta and fetal membranes. No significant differences in newborn parameters of either smoker or non-smokers were observed, which may indicate women’s adaptation to the environment containing cigarette smoke. The placenta and fetal membranes are biomarkers of the level of toxic exposure for the developing baby.
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Keywords

heavy metals, Placenta, cadmium, lead

About this article
Title

Effects of the cigarette smoking on the newborn clinikal parametrs and the accumulation of cadmium and lead in the placenta of women from Upper Silesia

Journal

Ginekologia Polska

Issue

Vol 84, No 9 (2013)

DOI

10.17772/gp/1639

Bibliographic record

Ginekol Pol 2013;84(9).

Keywords

heavy metals
Placenta
cadmium
lead

Authors

Katarzyna Suprewicz
Iwona Kozikowska
Magdalena Chrobaczyńska-Dyląg
Anna Gał
Anna Piekarz
Jerzy Sikora
Helena Sławska
Robert Stawarz

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