Vol 7, No 1 (2021)
Review paper
Published online: 2021-05-20
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Mechanizm, działanie i skuteczność glikokortykosteroidów w polimialgii reumatycznej i olbrzymiokomórkowym zapaleniu tętnic –– czy te leki są zawsze skuteczne?

Bogna Grygiel-Górniak1, Agnieszka Szczepańska2, Marta Lubarska2, Włodzimierz Samborski1
DOI: 10.5603/FR.2021.0006
·
Forum Reumatologiczne 2021;7(1):27-34.
Affiliations
  1. Katedra i Klinika Reumatologii, Rehabilitacji i Chorób Wewnętrznych, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Fredry 10, 61-701 Poznań
  2. Rheumatology Research Group, Ortopedyczno-Rehabilitacyjny Szpital Kliniczny im W. Degi, ul. 28 Czerwca 1956 r. 135/147, 61-545 Poznań, Poland

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Vol 7, No 1 (2021)
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Published online: 2021-05-20

Abstract

W terapii polimialgii reumatycznej (PMR, polymialgia rheumatica) i olbrzymiokomórkowego zapalenia tętnic (GCA, giant cells arthritis) lekami pierwszego wyboru są glikokortykosteroidy (GKS). Powyższe choroby wymagają często wieloletniego leczenia, dlatego należy zwrócić szczególną uwagę na szerokie spektrum działań niepożądanych tych leków. Problemem, z którym można spotkać się w praktyce klinicznej, jest steroidooporność. W niniejszej publikacji zebrano najnowsze doniesienia naukowe dotyczących skuteczności terapii GKS w PMR współistniejącej (lub nie) z GCA.

Abstract

W terapii polimialgii reumatycznej (PMR, polymialgia rheumatica) i olbrzymiokomórkowego zapalenia tętnic (GCA, giant cells arthritis) lekami pierwszego wyboru są glikokortykosteroidy (GKS). Powyższe choroby wymagają często wieloletniego leczenia, dlatego należy zwrócić szczególną uwagę na szerokie spektrum działań niepożądanych tych leków. Problemem, z którym można spotkać się w praktyce klinicznej, jest steroidooporność. W niniejszej publikacji zebrano najnowsze doniesienia naukowe dotyczących skuteczności terapii GKS w PMR współistniejącej (lub nie) z GCA.

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Keywords

polimialgia reumatyczna; olbrzymiokomórkowe zapalenie tętnic; steroidoterapia

About this article
Title

Mechanizm, działanie i skuteczność glikokortykosteroidów w polimialgii reumatycznej i olbrzymiokomórkowym zapaleniu tętnic –– czy te leki są zawsze skuteczne?

Journal

Forum Reumatologiczne

Issue

Vol 7, No 1 (2021)

Article type

Review paper

Pages

27-34

Published online

2021-05-20

DOI

10.5603/FR.2021.0006

Bibliographic record

Forum Reumatologiczne 2021;7(1):27-34.

Keywords

polimialgia reumatyczna
olbrzymiokomórkowe zapalenie tętnic
steroidoterapia

Authors

Bogna Grygiel-Górniak
Agnieszka Szczepańska
Marta Lubarska
Włodzimierz Samborski

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