Islet after kidney transplantation

Abstract

Simultaneous pancreas and kidney transplantation is the best therapeutic option for patient with poorly controlled type 1 diabetes, end stage renal disease and with other secondary diabetic complications. However, when pancreas transplant is contraindicated or unavailable, pancreatic islet transplantation is alternative minimal-invasive procedure. It allows for improved and easier glucose control, prevent progression of secondary diabetic complications and improves quality of life. Here, we present two patients who receive an islet transplant some time after a kidney transplantation which led to improved glucose control, lower HbA1c, improved quality of life with stable and good kidney graft function.