Multinucleate cell angiohistiocytoma mimicking granuloma annulare — a case report
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Streszczenie
Background: Multinucleate cell angiohistiocytoma (MCAH) is an extremely rare fibrohistiocytic proliferation in the dermis with vascular hyperplasia, that has a benign but progressive course.
Aim of the study: The article aims to present MCAH, to increase awareness of this uncommon disease and to explicate the typical clinical and histopathologic features of this disorder.
Case report: A 57-year-old woman was admitted to the Department of Dermatology, with multiple reddish-brown to violaceous asymptomatic flattopped firm papules, plaques and nodules, located on the dorsum of her hands. The size of the lesions ranged from 5 mm to 2 cm in diameter. A biopsy from a skin lesion was taken. The histopathology result showed psoriasiform epidermal hyperplasia, massive vascular proliferation, and parallel collagen fibres. In addition, dispersed fibrohistiocytic partially multinucleated cells were found in the reticular layer of the dermis and immunohistochemistry revealed a contribution of mast cells.
Conclusions: In patients, especially women with violet-brown annular lesions on the dorsal of the hands, MCAH should be included in the differential diagnosis.
Słowa kluczowe: multinucleatecellangiohistiocytomaMCAHgranuloma annularemultinucleated cellannular lesions
Referencje
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