Intradermal injections of triamcinolone acetonide in Grahama-Little Syndrome treatment — case report
Abstract
Graham-Little-Piccardi-Lasseur syndrome (GLPLS) is a rare lichen planopillaris defined by scarring alopecia, loss of pubic and axillary hairs and progressive development of follicular papules located on the whole body. Topical or systemic corticosteroids, cysclosporine or hydroxychlorquina are the treatments usually proposed. We describe the effectiveness of intralesional triamcinolone acetonide in concentration of 8 mg/mL with oral acitretin 10 mg/day combined with topical 0.05% clobetasol propionate ointment in a patient with GLPLS. After 2 months of treatment, reduction of perifollicular erythema and follicular hyperkeratotic papules were observed with no new area of alopecia. We believe that intralesional triamcinolone acetonide could be an effective treatment by limiting the progression of the disease.
Keywords: Graham-Little-Piccardi-Lasseur syndromelichen planopilaristriamcinolone acetonide
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