Assessment of the effectiveness of Solverx® products — Atopic Forte cleansing emulsion and Atopic Forte body lotion in relieving the symptoms of atopic dermatitis

Abstract

Introduction: Atopic dermatitis (AD) is a chronic dermatosis characterized by the presence of typical erythematous lesions with lichenification, dry skin and accompanying itching. The mainstay of AD treatment is emollient therapy and avoidance of factors that aggravate skin lesions. The aim of the study was to evaluate the effectiveness of Atopic Forte Cleansing Emulsion and Solverx® Atopic Forte Body Lotion in relieving AD symptoms. Material and methods: The study group consisted of 50 patients (25 adults and 25 children) suffering from mild or moderate AD. At the beginning and after 2 weeks of use of the study products, the following measurements were made: transepidermal water loss (TEWL), sebum density and skin pH, the severity of skin lesions was assessed (IGA, Investigators’ Global Assessment) scale. Patients completed questionnaires regarding the patient’s preferences and satisfaction with the use of the products. Results: The mean TEWL level after 2 weeks of using the products significantly decreased (from 21.29 ± 7.02 to 13.93 ± 4.90 g/ h/m2, p = 0.0023), while the sebum density increased significantly (from 1.28 ± 1.05 to 2.48 ± 0.94 μg/cm2, p < 0.0001). The severity of skin lesions improved significantly (IGA: 1.70 ± 0.72 and 0.92 ± 0.67, p <0.0001, respectively). Patients in the questionnaires reported a reduction in symptoms (dryness, itching), restoration of skin comfort, with high tolerance of use. Conclusions: The Solverx® brand products — Atopic Forte Wash Emulsion and Atopic Forte Body Lotion reduce the severity of lesions and relieve symptoms in patients with mild and moderate atopic dermatitis.